SML3736

Hypoxia probe 2

95% (UPLC)

• Synonyme(s) : 5’-Methoxy-1’,2’-dimethyl-3-(1-((3-oxo-3H-phenoxazin-7-yl)oxy)ethyl)-1H-indole-4’,7’-dione
• Formule empirique (notation de Hill): C₂₅H₂₀N₂O₆
• Poids moléculaire : 444.44
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Pureté: 95% (UPLC)
• Forme: powder
• Conditions de stockage: protect from light
• Couleur: , Faint orange to red
• Solubilité: DMSO: 2 mg/mL, clear (Warmed)
• Conditions d'expédition: wet ice
• Température de stockage: -10 to -25°C

Description

Actions biochimiques/physiologiques

Hypoxia probe 2 is a resorufin-based non-fluorescent hypoxia probe that undergoes cytochrome P450 reductase (PH51)-catalyzed reduction to yield the fluorescent reporter resorufin (ex 545 nm, em 582 nm) in conditions of 4% O2 and lower, allowing imaging hypoxia levels similar to those detected by pimonidazole without the use of antibodies. When employed together with Tokyo green-based hypoxia probe 4 (Tokyo green ex 480 nm, em 515 nm), the probe pair allows the simultaneous (two-color) imaging of different hypoxia levels in living cells.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable