Unfortunately, the stability of this product in solution is not determined. However, other sources report that stock solutions in DMSO may be stable for 1 month at -20°C and 1 year at -80°C. This information has not been validated.
SML1169
Pitstop 2
≥98% (HPLC), powder, clathrin-mediated endocytosis inhibitor
Synonyme(s) :
N-[5-[(4-Bromophenyl)methylene]-4,5-dihydro-4-oxo-2-thiazolyl]-1-naphthalenesulfonamide, Pitstop-2
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About This Item
Formule empirique (notation de Hill):
C20H13BrN2O3S2
Numéro CAS:
Poids moléculaire :
473.36
Code UNSPSC :
12352200
Nomenclature NACRES :
NA.77
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Nom du produit
Pitstop 2, ≥98% (HPLC)
Niveau de qualité
Essai
≥98% (HPLC)
Forme
powder
Couleur
white to light brown
Solubilité
DMSO: 20 mg/mL, clear
Température de stockage
−20°C
Actions biochimiques/physiologiques
Pitstop 2 also has an ability to breakdown the nuclear pore complex (NPC) permeability barrier and decrease importin β binding along with alteration of the NPC ultrastructure.[3] Pitstop 2 is also involved in the inhibition of platelet activation, platelet aggregation and secretion.[4]
Pitstop 2 is a selective inhibitor of clathrin-mediated endocytosis that acts via blocking ligand access to the clathrin terminal domain. Pitstop 2 selectively inhibits clathrin-mediated HIV entry and stalls clathrin-coated pit (CCP) dynamics.
Pitstop 2 is a selective inhibitor of clathrin-mediated endocytosis.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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Hello, how long this product lasts in -20C after is reconstituted in DMSO?
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