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Key Documents

SAB5300165

Sigma-Aldrich

Monoclonal Anti-OVA antibody produced in mouse

clone 3G2E1D9, ascites fluid

Synonyme(s) :

N/A

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

mouse

Conjugué

unconjugated

Forme d'anticorps

ascites fluid

Type de produit anticorps

primary antibodies

Clone

3G2E1D9, monoclonal

Technique(s)

direct ELISA: 1:10,000
western blot: 1:500-1:2,000

Isotype

IgG1

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Description générale

Ovalbumin (323-339) is an egg white protein surrounded by B-cell epitopes, which are bound by specific IgE antibodies. In addition to this, it also contains CD4+ T cell epitopes.

Immunogène

Ovalbumin
Mouse monoclonal antibody raised against OVA

Actions biochimiques/physiologiques

Ovalbumin (OVA) peptide 323-339 mediates 25-35% of T-cell response to intact OVA in isolated BALB/c mouse. OVA 323-339 has been widely used to determine the characteristics of class II major histocompatibility complex (MHC)-peptide binding and T-cell activation. It is extensively used in allergy research.

Forme physique

Ascitic fluid containing 0.03% sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

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Expression of non-self antigens by tumors can induce activation of T cells in vivo, although this activation can lead to either immunity or tolerance. CD8+ T-cell activation can be direct (if the tumor expresses MHC class I molecules) or indirect
Comparison between ovalbumin and ovalbumin peptide 323-339 responses in allergic mice: humoral and cellular aspects.
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Scandinavian Journal of Immunology, 71(5), 329-335 (2010)
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