SAB4501599

Anti-JAK2 antibody produced in rabbit

affinity isolated antibody

• Synonyme(s) : JAK-2, JAK2, Janus kinase 2, kinase Jak2
• Numéro MDL: MFCD00802820
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen 130 kDa
• Espèces réactives: mouse, rat, human
• Concentration: ~1 mg/mL
• Technique(s): ELISA: 1:5000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• Numéro d'accès NCBI: O60674
• Numéro d'accès UniProt: O60674
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... JAK2(3717)

Description

Description générale

Anti-JAK2 antibody detects endogenous levels of total JAK2 protein.

JAK2 (janus kinase 2) encodes a tyrosine kinase. It belongs to the the Jak family of proteins. It is located on human chromosome 9p24.

Immunogène

The antiserum was produced against synthesized peptide derived from human JAK2.

Immunogen Range: 541-590

Actions biochimiques/physiologiques

JAK2 (janus kinase 2) plays an important role in the activities of cytokines receptors. Overexpression of JAK2 results in neuroblastoma. JAK2 mutations promote primary resistance to PD-1 (anti-programmed death protein 1) blockade therapy.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): nwg
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable