SAB4501401

Anti-HMGB1 antibody produced in rabbit

affinity isolated antibody

• Synonyme(s) : HMG-1, HMG1, High mobility group protein 1, High mobility group protein B1
• Numéro MDL: MFCD02263062
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen 24 kDa
• Espèces réactives: rat, human, mouse
• Concentration: ~1 mg/mL
• Technique(s): ELISA: 1:20000; western blot: 1:500-1:1000
• Numéro d'accès NCBI: P09429
• Numéro d'accès UniProt: P09429
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... HMGB1(3146)

Description

Description générale

Anti-HMGB1 Antibody detects endogenous levels of total HMGB1 protein.

High mobility group box 1 (HMGB1) is a nuclear protein that belongs to the damage-associated molecular pattern (DAMP) family. It is located on human chromosome 13q12.

Immunogène

The antiserum was produced against synthesized peptide derived from human HMGB1.

Immunogen Range: 131-180

Actions biochimiques/physiologiques

High mobility group box 1 (HMGB1) is involved in bone remodeling and ectopic calcification pathogenesis. It initiates neuroinflammation after epileptogenic injuries. HMGB1 also binds to chromatin and modulates gene transcription.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): nwg
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable