S0375

D-Saccharic acid 1,4-lactone monohydrate

≥98.0% (HPLC)

• Synonyme(s) : D-Glucaric acid-1,4-lactone, D-Saccharolactone
• Formule empirique (notation de Hill): C₆H₈O₇ · H₂O
• Numéro CAS: 61278-30-6
• Poids moléculaire : 210.14
• Beilstein: 85594
• Numéro MDL: MFCD00149334
• Code UNSPSC : 12352201
• ID de substance PubChem : 24899420
• Nomenclature NACRES : NA.25

Propriétés

• Niveau de qualité: 200
• Essai: ≥98.0% (HPLC)
• Forme: powder
• Impuretés: ≤10.0% water (Karl Fischer)
• Couleur: white
• Pf: 91 - 93 °C ((196 - 199 °F ))
• Solubilité: water: 50 mg/mL, clear, colorless to faintly yellow
• Température de stockage: 2-8°C
• Chaîne SMILES: O.O[C@@H]1[C@@H](O)C(=O)O[C@@H]1[C@H](O)C(O)=O
• InChI: 1S/C6H8O7.H2O/c7-1-2(8)6(12)13-4(1)3(9)5(10)11;/h1-4,7-9H,(H,10,11);1H2/t1-,2-,3+,4+;/m1./s1
• Clé InChI: NPFKVZHSFSFLPU-QGBSHYGGSA-N

Description

Description générale

D-Saccharic acid 1,4-lactone monohydrate (DSAL) has an ability to inhibit the activity of β-glucuronidase enzyme.[1]It also potentially inhibits Klotho deglycosylation of excitatory amino acid transporters (EAATs) and peptide transporters (PEPTs).[2]

Application

D-Saccharic acid 1,4-lactone monohydrate has been used as a constituent of phosphate buffer to block incidental β-glucuronidase activity in Streptococcus pneumoniae hyaluronan lyase (SpnHL) activity assay.[3] It has also been used as a component of reaction mixture in Iduronidase activity assay[4] and UDP-glucuronosyltransferase 1 (UGT1A1) inhibition assay.[5]

Autres remarques

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)