M7765

1-Oleoyl-rac-glycerol

≥99%

• Synonyme(s) : MG(18:1(9Z)/0:0/0:0)[rac], 1-(cis-9-Octadecenoyl)-rac-glycerol, rac-Glycerol 1-monooleate, DL-α-Monoolein, Glyceryl cis-9-octadecenoate, Monoolein
• Formule linéaire : CH₃(CH₂)₇CH=CH(CH₂)₇COOCH₂CHOHCH₂OH
• Numéro CAS: 111-03-5
• Poids moléculaire : 356.54
• Numéro Beilstein : 1728976
• Numéro CE : 203-827-7
• Numéro MDL: MFCD00042735
• Code UNSPSC : 12352211
• ID de substance PubChem : 24897178
• Nomenclature NACRES : NA.25

Propriétés

• Source biologique: synthetic (organic)
• Description: non-ionic
• Pureté: ≥99%
• Forme: powder
• Pf: 35 °C
• Groupe fonctionnel: ester
• Type de lipide: neutral glycerides
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Chaîne SMILES: O=C(CCCCCCC/C=C\CCCCCCCC)OCC(O)CO
• InChI: 1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-
• Clé InChI: RZRNAYUHWVFMIP-KTKRTIGZSA-N

Description

Description générale

1-Oleoyl-rac-glycerol is a monoglyceride, obtained from natural oils and fats. It contains two alcohol groups that are reactive. It is soluble in chloroform and hexane. It can be crystallized from hexane.

Application

1-Oleoyl-rac-glycerol has been used:

• to mix with the sample by two-syringe method, to achieve lipidic cubic phase in crystallization technique
• as a substrate for monoglyceride (MG) lipase assay
• in the preparation of MG solution for the measurement of in vitro MG hydrolase activity

Actions biochimiques/physiologiques

1-Oleoyl-rac-glycerol shows both inhibition and anti-inhibition action on the lipoprotein lipase mediated triglyceride hydrolysis.

Monoolein (1-Oleoyl-rac-glycerol) is used in the development of monoolein-based nanoparticulate liquid dispersions as possible vehicles for drug delivery.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 309.2 °F - closed cup
• Point d'éclair (°C): 154.0 °C - closed cup
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)