K8625

L-Kynurenine

≥98% (HPLC)

• Synonyme(s) : β-Anthraniloyl-L-alanine, L-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid
• Formule empirique (notation de Hill): C₁₀H₁₂N₂O₃
• Numéro CAS: 2922-83-0
• Poids moléculaire : 208.21
• Numéro MDL: MFCD00069912
• Code UNSPSC : 12352209
• ID de substance PubChem : 24896246
• Nomenclature NACRES : NA.26

Propriétés

• product name: L-Kynurenine, ≥98% (HPLC)
• Pureté: ≥98% (HPLC)
• Forme: powder
• Pf: 219 °C
• Application(s): detection
• Chaîne SMILES: N[C@@H](CC(=O)c1ccccc1N)C(O)=O
• InChI: 1S/C10H12N2O3/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15/h1-4,8H,5,11-12H2,(H,14,15)/t8-/m0/s1
• Clé InChI: YGPSJZOEDVAXAB-QMMMGPOBSA-N

Description

Application

L-Kynurenine has been used as a standard for indoleamine-2,3-dioxygenase (IDO) assay. It has also been used as a standard to extract and quantify kynurenine from cultured cells and media.

Actions biochimiques/physiologiques

L-Kynurenine is a key intermediate in the breakdown of L-tryptophan and the formation of nicotinamide adenine dinucleotide (NAD+) via the kynurenine pathway. It is involved in a variety of neurological processes and diseases. L-Kynurenine is a substrate for kynureninase/kynurenine hydrolase; kynurenine 3-monooxygenase and kynurenine-oxoglutarate transaminase.

Key intermediate in the breakdown pathway of tryptophan.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)