FLAAS

Adenosine 5′-triphosphate (ATP) disodium salt hydrate

vial of ~1 mg ATP

• Synonyme(s) : ATP disodium hydrate
• Formule linéaire : C₁₀H₁₄N₅O₁₃P₃Na₂ · xH₂O
• Numéro CAS: 34369-07-8
• Poids moléculaire : 551.14 (anhydrous basis)
• Numéro CE : 213-579-1
• Numéro MDL: MFCD00150755
• Code UNSPSC : 12352202
• eCl@ss : 32160414
• ID de substance PubChem : 24895005
• Nomenclature NACRES : NA.26

Propriétés

• Source biologique: bacterial (Corynebacterium sp)
• Pureté: ≥90%
• Forme: lyophilized powder
• Conditionnement: vial of ~1 mg ATP
• Température de stockage: −20°C
• Chaîne SMILES: Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O
• InChI: 1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1
• Clé InChI: NTBQNWBHIXNPRU-MSQVLRTGSA-L

Description

Application

Adenosine 5′-triphosphate (ATP) disodium salt hydrate has been:

• used as a standard to measure ATP by bioluminescence method
• used in kinase buffer to assess the interaction between death-associated protein kinases (DAPK2) and 14-3-3-β
• used as a standard in ATP colorimetric assay

Actions biochimiques/physiologiques

Adenosine 5′-triphosphate (ATP) is one of the nucleoside triphosphate present in living system. It controls various biologic processes such as glucose metabolism, muscle contraction and neurotransmission. Apart from this, ATP serves as an important energy source for the cell. Administration of ATP might be useful in the treatment of non-small-cell lung cancer.

Adenosine 5′-triphosphate was shown to have inhibitory effects on the inflammatory response by abrogating secretion of TNF-α and promoting secretion of Interleukin-10.

P₂ purinergic agonist; increases activity of Ca²⁺-activated K⁺ channels; substrate for ATP-dependent enzyme systems

Quantité

Each vial contains ~1.2 mg of Na₂ATP • 3H₂O equivalent to ~1.0 mg of ATP (2.0 μmol). Actual amount printed on the label.

Notes préparatoires

Prepared to be substantially vanadium-free.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)