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A propos de cet article
Form:
lyophilized powder
Biological source:
bovine milk
Service technique
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Laissez-nous vous aiderbiological source
bovine milk
form
lyophilized powder
usage
mg sufficient for ~4,000 assays
composition
Protein, 20-40% modified Warburg-Christian
technique(s)
ligand binding assay: suitable, surface plasmon resonance (SPR): suitable
capacity
1.5-6.0 μg/mg, protein binding capacity (folic acid)(25 °C at pH 7.5.)
storage temp.
−20°C
Application
Folate binding protein can be used in radioligand binding assays of serum folate. The folate receptor has been used in studies as a therapeutic target in a variety of cancers.
Useful for radioligand binding assays of serum folate. May also bind N-methyltetrahydrofolic acid and other folate analogues.
Folate binding protein from bovine milk has been used in folate binding studies using surface plasmon resonance and in the uptake studies in kidney proximal tubule cells.
Biochem/physiol Actions
Folate-binding protein (FBP) is present as a cell receptor and binds to folate in equimolar ratio. It is involved in the transport of folate and improves their bioavailability.
Packaging
Package size based on protein content
Physical form
Lyophilized powder containing buffer salt as sodium citrate
Analysis Note
Purified over 1,000 fold. May contain a trace of β-mercaptoethanol.
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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