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Merck

F0504

Folate binding protein from bovine milk

lyophilized powder

Synonyme(s) :

Folate Protein

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A propos de cet article

UNSPSC Code:
12352202
NACRES:
NA.61
MDL number:
Form:
lyophilized powder
Biological source:
bovine milk
Service technique
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biological source

bovine milk

form

lyophilized powder

usage

 mg sufficient for ~4,000 assays

composition

Protein, 20-40% modified Warburg-Christian

technique(s)

ligand binding assay: suitable, surface plasmon resonance (SPR): suitable

capacity

1.5-6.0 μg/mg, protein binding capacity (folic acid)(25 °C at pH 7.5.)

storage temp.

−20°C

Application

Folate binding protein can be used in radioligand binding assays of serum folate. The folate receptor has been used in studies as a therapeutic target in a variety of cancers.
Useful for radioligand binding assays of serum folate. May also bind N-methyltetrahydrofolic acid and other folate analogues.
Folate binding protein from bovine milk has been used in folate binding studies using surface plasmon resonance and in the uptake studies in kidney proximal tubule cells.

Biochem/physiol Actions

Folate-binding protein (FBP) is present as a cell receptor and binds to folate in equimolar ratio. It is involved in the transport of folate and improves their bioavailability.

Packaging

Package size based on protein content

Physical form

Lyophilized powder containing buffer salt as sodium citrate

Analysis Note

Purified over 1,000 fold. May contain a trace of β-mercaptoethanol.


Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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