D9286

Paraoxon-éthyle

≥90%, oil

• Synonyme(s) : Phosphate de O,O-diéthyl O-(4-nitrophényl), Phosphate de diéthyl p-nitrophényl
• Formule linéaire : O₂NC₆H₄OP(O)(OC₂H₅)₂
• Numéro CAS: 311-45-5
• Poids moléculaire : 275.20
• UNSPSC Code: 12352202
• NACRES: NA.77
• PubChem Substance ID: 24894279
• EC Number: 206-221-0
• Beilstein/REAXYS Number: 1915526
• MDL number: MFCD00007316

Propriétés

• Quality Segment: 100
• assay: ≥90%
• form: oil
• color: yellow
• refractive index: n20/D 1.51 (lit.)
• density: 1.274 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: CCOP(=O)(OCC)Oc1ccc(cc1)[N+]([O-])=O
• InChI: 1S/C10H14NO6P/c1-3-15-18(14,16-4-2)17-10-7-5-9(6-8-10)11(12)13/h5-8H,3-4H2,1-2H3
• InChI key: WYMSBXTXOHUIGT-UHFFFAOYSA-N
• Gene Information: human ... PON1(5444)

Description

Application

Paraoxon-ethyl has been used as a substrate in paraoxonase (PON) activity assay. It has also been used as a lipase inhibitor to study the effects of anacetrapib on homotypic transfer from high density lipoprotein L3 (HDL3) to HDL2 in vivo.

Biochem/physiol Actions

Potent irreversible acetylcholinesterase inhibitor

Physical form

Oily liquid

Disclaimer

air sensitive: handle under argon

Informations sur la sécurité

• Pictogrammes: GHS06,GHS09
• Mot-clé: Danger
• Codes de danger: H300 + H310,H410
• Mentions de précaution: P262 - P264 - P273 - P280 - P301 + P310 - P302 + P352 + P310
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 1 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• Classe de stockage: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• EPI (équipement de protection individuelle): Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter