D7400

2′-Deoxyadenosine monohydrate

≥99%

• Synonyme(s) : 9-(2-Deoxy-β-D-ribofuranosyl)adenine, Adenine deoxyriboside
• Formule empirique (notation de Hill): C₁₀H₁₃N₅O₃ · H₂O
• Numéro CAS: 16373-93-6
• Poids moléculaire : 269.26
• Numéro Beilstein : 91015
• Numéro CE : 213-488-7
• Numéro MDL: MFCD00005754
• Code UNSPSC : 41106305
• ID de substance PubChem : 24894129
• Nomenclature NACRES : NA.51

Propriétés

• Source biologique: synthetic (organic)
• Pureté: ≥99%
• Forme: powder
• Solubilité: water: 25 mg/mL, clear to slightly hazy, colorless to faintly yellow
• Température de stockage: 2-8°C
• Chaîne SMILES: [H]O[H].Nc1ncnc2n(cnc12)[C@H]3C[C@H](O)[C@@H](CO)O3
• InChI: 1S/C10H13N5O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,7+/m0/s1
• Clé InChI: OLXZPDWKRNYJJZ-RRKCRQDMSA-N

Description

Application

2′-Deoxyadenosine monohydrate has been used:

• as a component for nucleoside supplementation
• as a standard for to estimate DNA global methylation rate in proliferating oil palm embryogenic suspensions
• to reverse sterile alpha motif (SAM) and histidine-aspartate (HD) domain-containing protein (SAMHD1)
• inhibition of human immunodeficiency virus (HIV-1) and hepatitis B virus (HBV)

Actions biochimiques/physiologiques

2′-Deoxyadenosine (2′-dAdo), a deoxyribonucleoside, may be used by some cells as an energy source under energy stress conditions and to affect cAMP levels. 2′-dAdo is used in comparison studies of the functions of adenosine analogues on various biological processes.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Faceshields, Gloves