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Key Documents

D6277

Sigma-Aldrich

N-Decanoyl-N-methylglucamine

≥98% (GC)

Synonyme(s) :

N-(D-Glucityl)-N-methyldecanamide, N-Decanoyl-N-methyl-D-glucamine, MEGA-10

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About This Item

Formule empirique (notation de Hill):
C17H35NO6
Numéro CAS:
Poids moléculaire :
349.46
Numéro Beilstein :
6974359
Numéro MDL:
Code UNSPSC :
12161900
ID de substance PubChem :
Nomenclature NACRES :
NA.25

Description

non-ionic

Pureté

≥98% (GC)

Forme

powder

Poids mol.

349.46 g/mol

Technique(s)

ligand binding assay: suitable
protein purification: suitable

CMC

6-7 mM (20-25°C)

Température de stockage

2-8°C

Chaîne SMILES 

OCC(O)C(O)C(O)C(O)CN(C)C(CCCCCCCCC)=O

InChI

1S/C17H35NO6/c1-3-4-5-6-7-8-9-10-15(22)18(2)11-13(20)16(23)17(24)14(21)12-19/h13-14,16-17,19-21,23-24H,3-12H2,1-2H3

Clé InChI

UMWKZHPREXJQGR-UHFFFAOYSA-N

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Description générale

N-Decanoyl-N-methylglucamine is a nonionic detergent used in lysis buffers.

Application

N-Decanoyl-N-methylglucamine has been used in a study to assess the effect of surfactants on wetting behavior of super-hydrophobic surfaces. It has also been used in a study to investigate the clinical impact of Human metapneumovirus (hMPV) vaccines on Syrian golden hamsters.
Non-ionic, dialyzable detergent used for the solubilization of membrane proteins

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Consulter la Bibliothèque de documents

Khemraj Budachetri et al.
mBio, 11(4) (2020-07-30)
Ehrlichia chaffeensis is an obligatory intracellular bacterium that causes human monocytic ehrlichiosis, an emerging disease transmitted by the Lone Star tick, Amblyomma americanum. E. chaffeensis outer membrane protein entry triggering protein of Ehrlichia (EtpE) is necessary for bacterial entry into
Sander Herfst et al.
The Journal of general virology, 88(Pt 10), 2702-2709 (2007-09-18)
Human metapneumovirus (hMPV), a newly discovered paramyxovirus, is associated with acute respiratory-tract illness, primarily in young children, individuals with underlying disease and the elderly. Two genetic lineages of hMPV circulate around the world, and viruses from these two lineages demonstrate
R Mohammadi et al.
Langmuir : the ACS journal of surfaces and colloids, 20(22), 9657-9662 (2004-10-20)
The effect of surfactants on wetting behavior of super-hydrophobic surfaces was investigated. Super-hydrophobic surfaces were prepared of alkylketene dimer (AKD) by casting the AKD melt in a specially designed mold. Time-dependent studies were carried out, using the axisymmetric drop shape
C Carnero Ruiz et al.
Biomacromolecules, 8(8), 2497-2503 (2007-07-17)
The protein-surfactant system constituted by bovine serum albumin (BSA) and N-decanoyl-N-methylglucamide (MEGA-10) has been studied by using surface tension, steady-state fluorescence, and dynamic light scattering measurements. It was found that the presence of protein delays the surfactant aggregation, which was
R Hovik et al.
The Biochemical journal, 290 ( Pt 1), 97-102 (1993-02-15)
The activity of the enzyme acyl-CoA oxidase (EC 1.3.99.3) is influenced by detergents. At concentrations above the critical micellar concentration, Triton X-100, Triton X-114 and Thesit stimulate oxidase activity. Lower concentrations of Triton X-100 and Triton X-114 render the acyl-CoA

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