D3071
Dipeptidyl Peptidase IX human
recombinant, expressed in Sf9 cells
Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
About This Item
Code UNSPSC :
12352204
Nomenclature NACRES :
NA.54
Le tarif et la disponibilité ne sont pas disponibles actuellement.
Produits recommandés
Produit recombinant
expressed in Sf9 cells
Niveau de qualité
Forme
solution
Activité spécifique
≥250 units/μg protein
Conditions d'expédition
dry ice
Température de stockage
−70°C
Catégories apparentées
Application
Actions biochimiques/physiologiques
DPP IX is a member of the S9b family of dipeptidyl peptidases and cleaves the peptide hormones glucagon-like peptide-1, glucagon-like peptide-2, neuropeptide Y and peptide YY with marked kinetic differences compared with dipeptidyl peptidase IV. It has a role in regulating cell survival and proliferation through modulating molecular signaling cascades. Protein kinase B activation is significantly inhibited by human DPP9 overexpression in human hepatoma cells (HepG2 and Huh7) and human embryonic kidney cells (HEK293T)[1]. DPP9 is thought to influence cell-extracellular matrix interactions and may be involved in the regulation of tissue remodeling [2].
Propriétés physiques
Full length sequence with an N-terminal GST tag
Définition de l'unité
DPP IX is a member of the S9b family of dipeptidyl peptidases. and cleaves the peptide hormones glucagon-like peptide-1, glucagon-like peptide-2, neuropeptide Y and peptide YY with marked kinetic differences compared with dipeptidyl peptidase IV.
One unit will hydrolyze 1.0 picomole of H-Gly-Pro-AMC per minute at pH 7.5 at 25 deg °C
Forme physique
Supplied as a solution in 40 mM Tris-HCl pH 8.0, 110 mM NaCl, 2.2 mM KCl, 20% glycerol, 3 mM DTT, and 16 mM glutathione
Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 1
Faites votre choix parmi les versions les plus récentes :
Déjà en possession de ce produit ?
Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Denise M T Yu et al.
The FEBS journal, 273(11), 2447-2460 (2006-05-18)
The dipeptidyl peptidase IV gene family contains the four peptidases dipeptidyl peptidase IV, fibroblast activation protein, dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Dipeptidyl peptidase IV and fibroblast activation protein are involved in cell-extracellular matrix interactions and tissue remodeling. Fibroblast
Tsun-Wen Yao et al.
Molecular cancer research : MCR, 9(7), 948-959 (2011-05-31)
Dipeptidyl peptidase IV (DPP4), DPP8, DPP9, and fibroblast activation protein (FAP), the four proteases of the DPP4 gene family, have unique peptidase and extra-enzymatic activities that have been implicated in various diseases including cancers. We report here a novel role
Active Filters
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
Contacter notre Service technique
