B2185

Bisoprolol hemifumarate salt

≥98% (HPLC), solid

• Synonyme(s) : 1-[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]-2-propanol hemifumarate salt
• Formule empirique (notation de Hill): C₁₈H₃₁NO₄ · .5C₄H₄O₄
• Numéro CAS: 104344-23-2
• Poids moléculaire : 383.48
• Numéro MDL: MFCD00792743
• Code UNSPSC : 12352200
• ID de substance PubChem : 24724414
• Nomenclature NACRES : NA.77

Propriétés

• Pureté: ≥98% (HPLC)
• Forme: solid
• Couleur: white
• Solubilité: DMSO: >20 mg/mL
• Auteur: Teva
• Chaîne SMILES: OC(=O)\C=C\C(O)=O.CC(C)NCC(O)COc1ccc(COCCOC(C)C)cc1.CC(C)NCC(O)COc2ccc(COCCOC(C)C)cc2
• InChI: 1S/2C18H31NO4.C4H4O4/c2*1-14(2)19-11-17(20)13-23-18-7-5-16(6-8-18)12-21-9-10-22-15(3)4;5-3(6)1-2-4(7)8/h2*5-8,14-15,17,19-20H,9-13H2,1-4H3;1-2H,(H,5,6)(H,7,8)/b;;2-1+
• Clé InChI: VMDFASMUILANOL-WXXKFALUSA-N
• Informations sur le gène: human ... ADRB1(153)

Description

Application

Bisoprolol hemifumarate salt has been used as a β-adrenergic receptor (β-AR) antagonist in cardiac fibrosis mice model.

Actions biochimiques/physiologiques

Bisoprolol hemifumarate is useful in oral formulations due to its high bioavailability. It also shows long elimination half-life.

Cardioselective β₁-adrenoceptor antagonist.

Caractéristiques et avantages

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Teva. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informations sur la sécurité

• Pictogrammes: GHS08,GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302,H361fd,H373
• Conseils de prudence: P202 - P260 - P264 - P280 - P301 + P312 - P308 + P313
• Classification des risques: Acute Tox. 4 Oral - Repr. 2 - STOT RE 2
• Organes cibles: Heart
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves