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72779
Triclosan
Triclosan
97.0-103.0% (active substance, GC)
Synonyme(s) :
Triclosan, 5-Chloro-2-(2,4-dichlorophenoxy)phenol, Irgasan
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About This Item
Formule empirique (notation de Hill):
C12H7Cl3O2
Numéro CAS:
Poids moléculaire :
289.54
Beilstein:
2057142
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352132
ID de substance PubChem :
Nomenclature NACRES :
NA.85
Le tarif et la disponibilité ne sont pas disponibles actuellement.
Produits recommandés
Source biologique
synthetic
Niveau de qualité
Essai
97.0-103.0% (active substance, GC)
Forme
powder or crystals
Impuretés
≤0.1% Water (Karl Fischer)
Couleur
white
Pf
55-59 °C
Solubilité
1 M NaOH: 5% at 25 °C, faintly turbid to clear (colorless solution)
Spectre d'activité de l'antibiotique
fungi
Mode d’action
enzyme | inhibits
Chaîne SMILES
Oc1cc(Cl)ccc1Oc2ccc(Cl)cc2Cl
InChI
1S/C12H7Cl3O2/c13-7-1-3-11(9(15)5-7)17-12-4-2-8(14)6-10(12)16/h1-6,16H
Clé InChI
XEFQLINVKFYRCS-UHFFFAOYSA-N
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Description générale
Chemical structure: diphenyl ether derivative
Application
A component of cefsulodin-irgasan-novobiocin selection medium for Yersinia, a human pathogen that may contaminate animal-source food products.
Actions biochimiques/physiologiques
It is an inhibitor of the enoyl-ACP (acyl-carrier protein) reductase component of type II fatty acid synthase (FAS-II) in bacteria and Plasmodium. It also inhibits mammalian fatty acid synthase (FASN), and may have anticarcinogenic activity.
Autres remarques
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
Mention d'avertissement
Warning
Mentions de danger
Conseils de prudence
Classification des risques
Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
dust mask type N95 (US), Eyeshields, Gloves
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Lot/Batch Number
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Les clients ont également consulté
Kathleen Dittmann et al.
Antimicrobial resistance and infection control, 8, 122-122 (2019-08-02)
Recent publications have raised concerns of reduced susceptibilities of clinical bacterial isolates towards biocides. This study presents a comparative investigation of the susceptibility of livestock-associated Methicillin-resistant Staphylococcus aureus (LA-MRSA), hospital-acquired MRSA (HA-MRSA) and community-aquired MRSA (CA-MRSA) to the commonly used
Siamak P Yazdankhah et al.
Microbial drug resistance (Larchmont, N.Y.), 12(2), 83-90 (2006-08-23)
Triclosan is a widely used biocide that is considered as an effective antimicrobial agent against different microorganisms. It is included in many contemporary consumer and personal health-care products, like oral and dermal products, but also in household items, including plastics
Markus K Diener et al.
Lancet (London, England), 384(9938), 142-152 (2014-04-11)
Postoperative surgical site infections are one of the most frequent complications after open abdominal surgery, and triclosan-coated sutures were developed to reduce their occurrence. The aim of the PROUD trial was to obtain reliable data for the effectiveness of triclosan-coated
R M Davies et al.
Journal of clinical periodontology, 31(12), 1029-1033 (2004-11-25)
To compare the effectiveness of triclosan/copolymer and fluoride dentifrices in improving plaque control and gingival health. We searched the Cochrane Controlled Trials Register, MEDLINE (1986 to March 2003) and EMBASE (1986 to March 2003). Personal files and the reference lists
Anthony Blinkhorn et al.
British dental journal, 207(3), 117-125 (2009-08-08)
Dental caries and periodontal disease are the most common oral conditions experienced by adults today. The treatment of these diseases by the dental team can only be performed when patients attend dental practices. There is recognition that the preventive measures
Articles
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What is the Department of Transportation shipping information for this product?
1 answer-
Helpful?
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What is Product 72779, Irgasan, soluble in?
1 answer-
Per the chemicals encyclopedia published by the Royal Society of Chemistry, 12th edition, Entry# 9790, Irgasan is not soluble in water, but it is readily soluble in alkaline solutions and many organic solvents.
Helpful?
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What are other names besides Irgasan that Product 72779 may be referred to?
1 answer-
Irgasan may also be referred to as Triclosan and 5-Chloro-2-(2,4-dichlorophenoxy)phenol.
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