43410

β-Nicotinamide-adénine-dinucléotide hydrate

≥95% (HPLC)

• Synonyme(s) : β-DPN, β-NAD, Coenzyme 1, Cozymase, DPN, Diphosphopyridine nucléotide, NAD, Nadide
• Formule empirique (notation de Hill): C₂₁H₂₇N₇O₁₄P₂ · xH₂O
• Numéro CAS: 53-84-9
• Poids moléculaire : 663.43 (anhydrous basis)
• Numéro CE : 200-184-4
• Numéro MDL: MFCD00036253
• Code UNSPSC : 12352111
• eCl@ss : 39200202
• ID de substance PubChem : 57650177
• Nomenclature NACRES : NA.55

Propriétés

• Pureté: ≥95% (HPLC)
• Forme: powder or crystals
• Impuretés: ≤4% water
• Couleur: white to faint yellow
• Solubilité: H₂O: 0.1 g/mL at 20 °C, clear; H₂O: freely soluble
• Traces de cations: Ca: ≤200 mg/kg; Cd: ≤50 mg/kg; Co: ≤50 mg/kg; Cr: ≤50 mg/kg; Cu: ≤50 mg/kg; Fe: ≤50 mg/kg; K: ≤50 mg/kg; Mg: ≤100 mg/kg; Mn: ≤50 mg/kg; Na: ≤1000 mg/kg; Ni: ≤50 mg/kg; Pb: ≤50 mg/kg; Zn: ≤50 mg/kg
• Rapport des absorbances: A_{280/260 nm} 0.22 ±0.02; A_{250/260 nm} 0.83 ±0.03
• Température de stockage: −20°C
• Chaîne SMILES: NC1=NC=NC2=C1N=CN2.O[C@@H]3[C@@H](COP(O)(OP(OC[C@@H](O4)[C@@H](O)[C@@H](O)[C@H]4[N+]5=CC=CC(C(N)=O)=C5)([O-])=O)=O)OC[C@@H]3O
• InChI: 1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
• Clé InChI: BAWFJGJZGIEFAR-NNYOXOHSSA-N
• Informations sur le gène: human ... ESR1(2099) , ESR2(2100)

Description

Application

β-Nicotinamide adenine dinucleotide hydrate has been used as a component of fibroblast cell culture media. It has also been used to study the viability of the cartilage constructs.

β-Nicotinamide adenine dinucleotide hydrate was used as a test compound for studying the structure and electrochemical properties of NADH electrocatalysts.

Actions biochimiques/physiologiques

β-Nicotinamide adenine dinucleotide is a cofactor for alcohol dehydrogenase that serves as inhibitory neurotransmitter in visceral smooth muscle.

β-nicotinamide adenine dinucleotide (β-NAD) is a coenzyme present in most living cells. It is implicated in redox reactions and posttranslational modifications. β-NAD also acts as a substrate for various enzymes in several cellular processes.

Accepteur d'électrons

Conditionnement

Produit conditionné en fonction du poids solide.

Autres remarques

Il s′agit de la forme courante du NAD.

Informations sur la sécurité

• Code de la classe de stockage: 13 - Non Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)