00541

Ruthenium Red

for microscopy, 85.0-115.0% (calc. on dry basis, AT)

• Synonyme(s) : Ammoniated ruthenium oxychloride
• Formule linéaire : [(NH₃)₅RuORu(NH₃)₄ORu(NH₃)₅]Cl₆
• Numéro CAS: 11103-72-3
• Poids moléculaire : 786.35
• Numéro C.I. (Colour Index): 77800
• Numéro MDL: MFCD00011479
• Code UNSPSC : 12171500
• ID de substance PubChem : 329747091
• Nomenclature NACRES : NA.47

Propriétés

• Qualité: for microscopy
• Niveau de qualité: 100
• Pureté: 85.0-115.0% (calc. on dry basis, AT)
• Forme: powder
• Impuretés: ~5% water
• Solubilité: water: 10 mg/mL, clear to turbid
• εmax: ≥150 at 529-539 nm
• Application(s): diagnostic assay manufacturing; hematology; histology
• Température de stockage: room temp
• Chaîne SMILES: N.N.N.N.N.N.N.N.N.N.N.N.N.N.[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Ru++]O[Ru++]O[Ru++]
• InChI: 1S/6ClH.14H3N.2O.3Ru/h6*1H;14*1H3;;;;;/q;;;;;;;;;;;;;;;;;;;;;;3*+2/p-6
• Clé InChI: ZXYSDUPLHOJIOR-UHFFFAOYSA-H

Description

Description générale

Ruthenium red is an inorganic cationic dye. It is also known as ammoniated ruthenium oxychloride. It is a large coordination complex consisting of three metal atoms connected by bridging oxygens, in addition to multiple amine ligands.

Application

Ruthenium red is suitable for use in light microscopy to stain pectins. It is also used to stain glycosaminoglycans by employing a two-color staining method with alcian blue. It serves as a typical basic dye at a higher pH that stains nuclei, Nissl substance, cartilage matrix, and mast cell granules. Other applications involving light microscopy include staining resin-embedded material. Ruthenium red is an important component of fixatives of the bacterial glycocalyx.

Inhibits mitochondrial Ca²⁺ uniporter; capsaicin antagonist; blocks VR1 vanilloid receptor-coupled ion channels.

Actions biochimiques/physiologiques

Ruthenium red inhibits mitochondrial Ca2+ uniporter. It is a known capsaicin antagonist. Additionally, it is known to block VR1 vanilloid receptor-coupled ion channels.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302
• Conseils de prudence: P264 - P270 - P301 + P312 - P501
• Classification des risques: Acute Tox. 4 Oral
• Code de la classe de stockage: 13 - Non Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable