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Y0000845

Atropine for peak identification

Name: Atropine for peak identification
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

Atropine, Hyoscyamine, Tropine tropate, endo-(±)-α-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester

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About This Item

Formule empirique (notation de Hill):

C₁₇H₂₃NO₃

Numéro CAS:

51-55-8

Poids moléculaire :

289.37

Beilstein:

91260

Numéro CE :

200-104-8

Numéro MDL:

MFCD00022622

Code UNSPSC :

41116107

ID de substance PubChem :

329831185

Nomenclature NACRES :

NA.24

Le tarif et la disponibilité ne sont pas disponibles actuellement.

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Atropine impurity B

Y0002000

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USP

1435003

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Sigma-Aldrich

A0257

Atropine sulfate salt monohydrate

USP

1044990

Atropine

Qualité

pharmaceutical primary standard

Famille d'API

atropine

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES

CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3

InChI

1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16?

Clé InChI

RKUNBYITZUJHSG-SPUOUPEWSA-N

Informations sur le gène

human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131)

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Catégories apparentées

Matériaux de référence analytiques destinés au contrôle qualité (QC) pharmaceutique

Étalons des instituts de métrologie et des pharmacopées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Atropine for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Actions biochimiques/physiologiques

Competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit

Description

Tarif

Mention d'avertissement

Danger

Mentions de danger

H300 + H330

Conseils de prudence

P260 - P264 - P271 - P284 - P304 + P340 + P310 - P403 + P233

Classification des risques

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

Code de la classe de stockage

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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1045009

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Sigma-Aldrich

A0257

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Incidence, pathophysiology, and treatment of complications during dobutamine-atropine stress echocardiography.

Marcel L Geleijnse et al.

Circulation, 121(15), 1756-1767 (2010-04-21)

Bradycardia during critical care intubation: mechanisms, significance and atropine.

Peter Jones et al.

Archives of disease in childhood, 97(2), 139-144 (2011-05-31)

Bradycardia occurs during the intubation of some critically ill children as a result of vagal stimulation due to hypoxia and/or laryngeal stimulation; such 'stable' bradycardia is accompanied by selective vasoconstriction. Some induction drugs also induce bradycardia which may be accompanied

Prognostic value of dobutamine-atropine stress echocardiography for peri-operative and late cardiac events in patients scheduled for vascular surgery.

D Poldermans et al.

European heart journal, 18 Suppl D, D86-D96 (1997-06-01)

Cardiac events in the peri-operative phase and late after non-cardiac vascular surgery are a major cause of morbidity and mortality. Numerous tests and diagnostic strategies--usually consisting of a combination of analysis of clinical risk factors and additional non-exercise dependent stress

Purinergic control of vascular tone in the retina.

Joanna Kur et al.

The Journal of physiology, 592(3), 491-504 (2013-11-28)

Purinergic control of vascular tone in the CNS has been largely unexplored. This study examines the contribution of endogenous extracellular ATP, acting on vascular smooth muscle cells, in controlling vascular tone in the in vivo rat retina. Retinal vessels were

Superficial layer pyramidal cells communicate heterogeneously between multiple functional domains of cat primary visual cortex.

Kevan A C Martin et al.

Nature communications, 5, 5252-5252 (2014-10-25)

The axons of pyramidal neurons in the superficial layers of the neocortex of higher mammals form lateral networks of discrete clusters of synaptic boutons. In primary visual cortex the clusters are reported to link domains that share the same orientation

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