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E0900000

Ergocalciferol

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

Ergocalciférol, Ergostérol irradié, « Ergostérol irradié »

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About This Item

Formule empirique (notation de Hill):
C28H44O
Numéro CAS:
Poids moléculaire :
396.65
Numéro Beilstein :
1916682
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Source biologique

synthetic

Qualité

pharmaceutical primary standard

Agence

EP

Famille d'API

ergocalciferol

Forme

solid

Fabricant/nom de marque

EDQM

Technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Pf

114-118 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

−20°C

Chaîne SMILES 

CC(C)[C@@H](C)/C=C/[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CCC/2)([H])C2=C\C=C(C[C@@H](O)CC3)/C3=C

InChI

1S/C28H44O/c1-19(2)20(3)9-10-22(5)26-15-16-27-23(8-7-17-28(26,27)6)12-13-24-18-25(29)14-11-21(24)4/h9-10,12-13,19-20,22,25-27,29H,4,7-8,11,14-18H2,1-3,5-6H3/b10-9+,23-12+,24-13-/t20-,22+,25-,26+,27-,28+/m0/s1

Clé InChI

MECHNRXZTMCUDQ-RKHKHRCZSA-N

Informations sur le gène

human ... VDR(7421)

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Ergocalciferol is a form of vitamin D, synthesized by some plants in the presence of UVB light. It can be obtained from diet intake or supplements.

Application

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Pictogrammes

Skull and crossbonesHealth hazard

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - STOT RE 1 Oral

Code de la classe de stockage

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Lot/Batch Number

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Consulter la Bibliothèque de documents

Simultaneous determination of cholecalciferol (vitamin D3) and ergocalciferol (vitamin D2) in foods by selected reaction monitoring
Dimartino G
Journal of AOAC (Association of Official Analytical Chemists) International, 92(2), 511-517 (2002)
Nutrition in the Prevention and Treatment of Disease (2008)
Jean-Yves Reginster
Current medical research and opinion, 21(4), 579-586 (2005-05-19)
Inadequate serum vitamin D is associated with secondary hyperparathyroidism, increased bone turnover, and bone loss, which increased fracture risk. Osteomalacia has also been observed in severe cases. Indeed, vitamin D and calcium are essential components of management strategies for the
Nirav Shah et al.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 25(4), 362-366 (2005-07-19)
Peritoneal dialysis (PD) patients are at risk for 25(OH) vitamin D deficiency due to effluent loss in addition to traditional risk factors. To measure 25(OH) vitamin D deficiency in prevalent PD patients, to evaluate a replacement dose, and to determine
Pentti Tuohimaa et al.
International journal of cancer, 108(1), 104-108 (2003-11-18)
Vitamin D inhibits the development and growth of prostate cancer cells. Epidemiologic results on serum vitamin D levels and prostate cancer risk have, however, been inconsistent. We conducted a longitudinal nested case-control study on Nordic men (Norway, Finland and Sweden)

Protocoles

Ascentis Express C18 is suitable for routine analysis of fat-soluble vitamins D2 and D3, providing optimized chromatograms.

Ascentis Express C18 is suitable for routine analysis of fat-soluble vitamins D2 and D3, providing optimized chromatograms.

Ascentis Express C18 is suitable for routine analysis of fat-soluble vitamins D2 and D3, providing optimized chromatograms.

Separation of Ergocalciferol (D2), analytical standard; Cholecalciferol (D3), analytical standard

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