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Merck
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Principaux documents

S1-M

Sigma-Aldrich

Human Serum, Normal

Synonyme(s) :

Normal Human Serum

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About This Item

Code UNSPSC :
41105901
eCl@ss :
26020100
Nomenclature NACRES :
NA.71
Source biologique:
human
Le tarif et la disponibilité ne sont pas disponibles actuellement.

Source biologique

human

Forme d'anticorps

serum

Fabricant/nom de marque

Chemicon®

Technique(s)

blocking: suitable (interfering antibodies)

Description générale

Normal human serum collected off the clot from healthy normal humans. Each donor unit was tested and found negative for HIV 1&2, HIV-Ag, HCV, HBsAg, and RPR by FDA approved methods.

Application

Normal Human Serum has been used as a reference or control in degradation assays involving DNase I and MNase treatments, providing a comparison for assessing the impact of these enzymes on the DHM structures.[1]

Forme physique

Nonsterile liquid. Contains no preservatives.

Filtered through a 0.2μ absolute membrane filter before bottling.

Stockage et stabilité

Store frozen at -20°C for up to 12 months. Avoid repeated freeze/thaw cycles.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Ce produit, destiné à la recherche scientifique, est soumis à une réglementation spécifique en France, y compris pour les activités d′importation et d′exportation (Article L 1211-1 alinéa 2 du Code de la Santé Publique). L′acheteur (c′est-à-dire l′utilisateur FINAL) est tenu d′obtenir une autorisation d′importation auprès du ministère français de la recherche, mentionné à l′article L1245-5-1 II du Code de la Santé Publique. En commandant ce produit, vous confirmez détenir l′autorisation d′importation requise.

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Midori L Wasielewski et al.
International journal of molecular sciences, 24(4) (2023-02-26)
This study analyzed the nuclease- and serum-driven degradation of millimeter-scale, circular DNA-histone mesostructures (DHMs). DHMs are bioengineered chromatin meshes of defined DNA and histone compositions designed as minimal mimetics of physiological extracellular chromatin structures, such as neutrophil extracellular traps (NETs).

Questions

1–6 of 6 Questions  

  1. Is dialyzed human serum available?

    1 answer

    1. Dialyzed serum is not sold as a product. However, normal human serum (cat #s S1-LITER or S1-100ML) is available.
      Additionally, we provide various products that allow the client to dialyze the serum. Depending on the volume of serum to be dialyzed, any of the following products will work:
      •D-Tubes or Amicon Ultra for small volumes
      •Centricon Plus-70 for centrifuging 70 mL samples (cat # UFC701008)
      •Stirred cells along with 10 kDa MWCO ultrafiltration membrane discs for volumes up to 400 mL

      Helpful?

  2. Is the product "Human Serum, Normal (S1-100ML)" Male only, Female only or Male/Female mix?

    1 answer

    1. This product is pooled human serum, typically consisting of hundreds of male and female donors.

      Helpful?

  3. Is there any detectable thrombin in this serum?

    1 answer

    1. Unfortunately, this product is not tested for thrombin.

      Helpful?

  4. Hi, wonder if this is a pooled serum from multiple donors or a single bottle is from a single donor? thanks.

    1 answer

    1. This serum product is pooled from multiple donors. The typical batch varies but can range from 400 to 500 donors.

      Helpful?

  5. I would like to know whether it has been inactivated as I intend to use the complement components in the serum to activate the complement system in vitro. Additionally, does this serum have been previously used in complement activation studies？

    1 answer

    1. This product has not been inactivated, however it is not tested for use in compliment studies. The product may or may not be suitable for this application. See the link below for a product that may be of interest:
      https://www.sigmaaldrich.com/product/sigma/c9473.

      Helpful?

  6. Hi! I was wondering how this serum is collected and what storage agents/additives were used in the collection tubes/bags. E.g. silica in Vacutainer SST tubes

    1 answer

    1. As it states in the "Description" section, normal human serum is collected off the clot from healthy normal humans. It is a nonsterile liquid with no preservatives.

      Helpful?

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