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Merck
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Principaux documents

MAB821

Sigma-Aldrich

Anti-Herpes Simplex Virus I & II Antibody, clone 4F10.3

clone 4F10.3, Chemicon®, from mouse

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Le tarif et la disponibilité ne sont pas disponibles actuellement.

Source biologique

mouse

Niveau de qualité

300

Forme d'anticorps

purified immunoglobulin

Clone

4F10.3, monoclonal

Espèces réactives

human

Fabricant/nom de marque

Chemicon®

Technique(s)

ELISA: suitable
immunofluorescence: suitable

Isotype

IgG2a

Conditions d'expédition

wet ice

Spécificité

Checked by immunoenzymatic method and shown to be highly reactive to HSV-I strains "Mac" and "F", moderately reactive to HSV-II strain "G" and weakly reactive to HSV-II strain "Ms". Possible application: direct detection of HSV I and HSV II virus.

Application

Detect Herpes Simplex Virus I & II using this Anti-Herpes Simplex Virus I & II Antibody, clone 4F10.3 validated for use in ELISA & IF.
ELISA Type I 1:6400 Type II 1:100

IFA infected fibroblasts 1:800

Final working dilutions must be determined by end user.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral

Forme physique

Format: Purified
Purified immunoglubulin. Liquid in 0.02M PB with 0.25M NaCl.pH=7.6, 0.1% Sodium Azide.

Stockage et stabilité

Maintain at 2-8°C.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Jianyun Liu et al.
Immunology, 140(2), 191-201 (2013-05-29)
CD1d-restricted T (natural killer T; NKT) cells are important for controlling herpesvirus infections. Interestingly, herpes simplex virus (HSV) can down-regulate CD1d-mediated activation of NKT cells. We have previously shown that the Thr322 residue in the cytoplasmic tail of human CD1d
J M McSharry et al.
Journal of clinical microbiology, 36(4), 958-964 (1998-05-23)
A flow cytometric assay has been developed for the measurement of susceptibilities to ganciclovir of laboratory strains and clinical isolates of human cytomegalovirus (HCMV). The assay uses fluorochrome-labeled monoclonal antibodies to HCMV immediate-early and late antigens to identify HCMV-infected cells

Questions

  1. How does it help for a herpes positive patient does it cure permanently Does it prevent from recurring episodes of herpes ?

    1 answer

    1. Product MAB821 cannot be used to treat human herpes. The product as shipped can contain up to 1% sodium azide - which is a highly toxic chemical

      Monoclonal antibodies can be used for a variety of widely different uses. Product MAB821 is intended only validated for use in ELISA & Immunofluorescent laboratory procedures. The antibody is not approved by the Food and Drug Administration for the treatment of human herpes. Check with your primary care doctor to determine if a monoclonal antibody treatment is available for the treatment of human herpes. Not every disease has an approved monoclonal antibody treatment available

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