ABS482
Anti-Perilipin-3, C-terminus Antibody
from rabbit, purified by affinity chromatography
Synonyme(s) :
Perilipin-3, Cargo selection protein TIP47, Mannose-6-phosphate receptor-binding protein 1
Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
rabbit
Niveau de qualité
Forme d'anticorps
affinity isolated antibody
Type de produit anticorps
primary antibodies
Clone
polyclonal
Produit purifié par
affinity chromatography
Espèces réactives
mouse
Technique(s)
immunocytochemistry: suitable
western blot: suitable
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
wet ice
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
mouse ... Plin3(66905)
Description générale
Perilipin-3, also known as Cargo selection protein TIP47, or Placental protein 17, PP17, 47 kDa mannose 6-phosphate receptor-binding protein, 47 kDa MPR-binding protein, also known as Mannose-6-phosphate receptor-binding protein 1, and encoded by the gene PLIN3/M6prbp1/Tip47, is a peripheral membrane protein that is required for the transport of mannose 6-phosphate receptors (MPR) from the endosomes to the trans-Golgi network. Perilipin 3 is part of the Perilipin family of proteins which are proteins that decorate the surface of cytosolic lipid droplets and play important roles in lipid metabolism. Cytosolic lipid droplets are now recognized as multifunctional organelles that, among other things, can accumulate in leukocytes under various inflammatory conditions. Perilipin-3 seems to play a critical role in the formation of lipid droplets and production of the the prostaglandin PGE2 an important inflammatory compound.
Immunogène
Epitope: C-terminus
Linear peptide corresponding to the C-terminus of mouse Perilipin-3, C-terminus.
Application
Immunocytochemistry Analysis: A representative lot detected Perilipin-3, C-terminus in OP9 cells (Skinner, J. R., et al. (2009). J Biol Chem. 284(45):30941-30948).
Research Category
Signaling
Signaling
Research Sub Category
Signaling Neuroscience
Signaling Neuroscience
This Anti-Perilipin-3 antibody, C-terminus is validated for use in western blotting & ICC for the detection of Perilipin-3.
Qualité
Evaluated by Western Blotting in NIH/3T3-L1 cell lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Perilipin-3, C-terminus in 10 µg of NIH/3T3-L1 cell lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Perilipin-3, C-terminus in 10 µg of NIH/3T3-L1 cell lysate.
Description de la cible
~ 52 kDa observed
Forme physique
Affinity purified
Purified rabbit polyclonal in buffer containing PBS without preservatives with 10% glycerol.
Stockage et stabilité
Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
Autres remarques
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Vous ne trouvez pas le bon produit ?
Essayez notre Outil de sélection de produits.
Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
Déjà en possession de ce produit ?
Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Sophie Hiel et al.
Nutrients, 10(5) (2018-04-26)
Postprandial hyperlipidemia is an important risk factor for cardiovascular diseases in the context of obesity. Inulin is a non-digestible carbohydrate, known for its beneficial properties in metabolic disorders. We investigated the impact of inulin on postprandial hypertriglyceridemia and on lipid
Amin Khalifeh-Soltani et al.
JCI insight, 1(18), e87418-e87418 (2016-11-05)
The small intestine has an underappreciated role as a lipid storage organ. Under conditions of high dietary fat intake, enterocytes can minimize the extent of postprandial lipemia by storing newly absorbed dietary fat in cytoplasmic lipid droplets. Lipid droplets can
Mika Yamada et al.
Journal of lipid research, 63(5), 100194-100194 (2022-03-15)
Lipid droplets (LDs) are multifunctional organelles that regulate energy storage and cellular homeostasis. The first step of triacylglycerol hydrolysis in LDs is catalyzed by adipose triglyceride lipase (ATGL), deficiency of which results in lethal cardiac steatosis. Although hormone-sensitive lipase (HSL)
MIGA2 Links Mitochondria, the ER, and Lipid Droplets and Promotes De Novo Lipogenesis in Adipocytes.
Christophe A C Freyre et al.
Molecular cell, 76(5), 811-825 (2019-10-20)
Physical contact between organelles is vital to the function of eukaryotic cells. Lipid droplets (LDs) are dynamic organelles specialized in lipid storage that interact physically with mitochondria in several cell types. The mechanisms coupling these organelles are, however, poorly understood
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
Contacter notre Service technique