8.20128

Saccharin

for synthesis

• Synonyme(s) : Saccharin
• Formule empirique (notation de Hill): C₇H₅NO₃S
• Numéro CAS: 81-07-2
• Poids moléculaire : 183.18
• Numéro MDL: MFCD00005866
• Code UNSPSC : 12352115
• Numéro de classement CE : 201-321-0
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 200
• Pureté: ≥98.0% (acidimetric)
• Forme: crystals
• Pf: 228-230 °C
• Température de stockage: 2-30°C
• InChI: 1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9)
• Clé InChI: CVHZOJJKTDOEJC-UHFFFAOYSA-N

Description

Application

• Gabapentin-saccharin co-crystals with enhanced physicochemical properties and in vivo absorption formulated as oro-dispersible tablets.: This study presents the formulation of gabapentin-saccharin co-crystals, demonstrating improved solubility and absorption, beneficial for pharmaceutical applications (Soliman et al., 2020, doi: 10.1080/10837450.2019.1687521).


• Improving the solubility, dissolution, and bioavailability of Ibrutinib by preparing it in a coamorphous state with saccharin.: The research focuses on enhancing the bioavailability of Ibrutinib through coamorphous preparation with saccharin, which is significant for cancer treatment (Shi et al., 2019, doi: 10.1016/j.xphs.2019.04.031).

Remarque sur l'analyse

Assay (acidimetric): ≥ 98.0 %
Melting range (lower value): ≥ 226 °C
Melting range (upper value): ≤ 230 °C
Identity (IR): passes test

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable