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420355

Sigma-Aldrich

Isoprenaline hydrochloride

≥99% (TLC), solid, β-adrenoceptor agonist, Calbiochem

Synonyme(s) :

Isoproterenol, Hydrochloride

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About This Item

Formule empirique (notation de Hill):
C11H17NO3 · xHCl
Numéro CAS:
51-30-9
Poids moléculaire :
211.26 (free base basis)
Numéro MDL:
MFCD00012603
Code UNSPSC :
12352200
Nomenclature NACRES :
NA.77

product name

Isoproterenol, Hydrochloride, Phenethylamine derivative.

Niveau de qualité

100

Pureté

≥99% (TLC)

Forme

solid

Fabricant/nom de marque

Calbiochem®

Conditions de stockage

OK to freeze
protect from light

Couleur

white to off-white
 white

Solubilité

ethanol: soluble
water: soluble

Conditions d'expédition

ambient

Température de stockage

10-30°C

InChI

1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H

Clé InChI

IROWCYIEJAOFOW-UHFFFAOYSA-N

Description générale

Phenethylamine derivative. Selective β-adrenergic agonist that increases cytosolic cAMP. Promotes glycogen breakdown and causes bronchodilation. Increases Cl- diffusion and potential difference in rabbit trachea cells through nitric oxide generation.
Phenethylamine derivative. Selective β-adrenergic agonist that stimulates adenylate cyclase activity. Promotes glycogen breakdown and causes bronchodilation. Increases Cl– diffusion and potential difference in rabbit trachea cells through nitric oxide generation. Reported to activate MAP Kinase (ERK) by a Rap1 and B-Raf dependent process.

Actions biochimiques/physiologiques

Cell permeable: no
Primary Target
β-adrenergic agonist
Product does not compete with ATP.
Reversible: no

Avertissement

Toxicity: Irritant (B)

Reconstitution

Unstable in solution; reconstitute just prior to use.

Autres remarques

Schmitt, J.M., and Stork, P.J. 2000. J. Biol. Chem.275, 25342.
Carmena, M.J., et al. 1997. Prostate 33, 46.
Takemura, H., et al. 1995. J. Pharmacol. Exp. Ther. 274, 584.
Kishimoto, I., et al. 1994. J. Biol. Chem.269, 28300.
Macaulay, S.L., et al. 1994. Mol. Cell Biochem.141, 27.
Yashiro, K., et al. 1994. J. Biochem.115, 1040.
Ladenheim, R.G., et al. 1993. J. Neurochem.60, 260.
von Zastrow, M., et al. 1993. J. Biol. Chem.268, 763.
Mokhtari, A., et al. 1985. J. Cyclic Nucleotide Protein Phosphorylation Res.10, 213.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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