368057

Granzyme B Substrate I, Colorimetric

Colorimetric substrate for the detection of granzyme B and caspase-8 activity.

• Synonyme(s) : Granzyme B Substrate I, Colorimetric, Ac-IETD- pNA, Caspase-8 Substrate I, Ac-IETD-pNA, Caspase-8 Substrate I
• Formule empirique (notation de Hill): C₂₇H₃₈N₆O₁₂
• Poids moléculaire : 638.62
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Pureté: ≥95% (HPLC)
• Forme: lyophilized solid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; protect from light
• Couleur: white
• Solubilité: DMSO: 5 mg/mL
• Conditions d'expédition: ambient
• Température de stockage: −20°C

Description

Description générale

Colorimetric substrate for detection of granzyme B. Cleavage is monitored colorimetrically at ~405 nm.

Colorimetric substrate for the detection of granzyme B and caspase-8 activity. Cleavage of pNA is monitored colorimetrically at ~405 nm.

Actions biochimiques/physiologiques

Cell permeable: no

Primary Target
Colorimetric substrate for the detection of granzyme B and caspase-8 activity

Product does not compete with ATP.

Reversible: no

Avertissement

Toxicity: Standard Handling (A)

Séquence

Ac-Ile-Glu-Thr-Asp-pNA

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Autres remarques

Koeplinger, K.A., et al. 2000. Protein Exp. Purif. 18, 378.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable