1.16887

Fractogel^® EMD TMAE (S)

• Synonyme(s) : Biochromatography, Fractogel^® Ion exchangers, Ion exchanger for LC (Fractogel^® TSK/EMD), Fractogel^® EMD TMAE (S)
• Code UNSPSC : 41115711

Propriétés

• ligand: (Trimethylammoniumethyl)
• Niveau de qualité: 400
• Description: strong anion exchanger, suspension in 20% ethanol and 150 mM NaCl (20-40 µm)
• Stérilité: sterile (Caustic Stable)
• Gamme de produits: Fractogel^®
• Forme: resin
• Paramètres: 8 bar max. pressure; 80 cm/hr flow rate
• Groupe de la matrice active: methacrylate
• Capacité: 100 mg binding capacity (BSA/mg of resin)
• Température de transition: flash point 35 °C (calculated)
• Densité: 1.430 g/cm³ at 20 °C
• Masse volumique apparente: 1000 kg/m³
• Application(s): gene therapy; recombinant protein; vaccine development
• Technique de séparation: anion exchange; strong anion exchange
• Température de stockage: 2-30°C

Description

Description générale

Stron anion exchange Fractogel^® resin with small particle size, featuring the tentacle technology with a trimethylammoniumethyl functional group, for purification of acidic and neutral proteins and peptides from multiple sources, DNA and virus removal, plasmid isolation, vaccine purification, and more

Caractéristiques et avantages

Fractogel^® EMD TMAE (S) (20-40 µm particle size) enables:

High protein loading conditions resulting in good selectivity and resolution with the tentacle technology

• Excellent binding to large viruses at increased loading
• Homogenous binding with high selectivity and purity
• Reduce operating costs and resin replacement with enduring durability - allowing for multiple cycles of column regeneration and sanitization
• Compatibility with 2.5 % (v/v) aqueous benzyl alcohol containing 150 mM NaCl storage solution

Conditionnement

• 1.16887.0100: Fractogel^® EMD TMAE (S) Resin 100ml
• 1.16887.0010: Fractogel^® EMD TMAE (S) Resin 10ml
• 1.16887.0500: Fractogel^® EMD TMAE (S) Resin 500ml
• 1.16887.5000: Fractogel^® EMD TMAE (S) Resin 5L

Plastic bottle

Remarque sur l'analyse

Appearance: Milky turbid suspension, free from impurities (foreign particles)
Microscopic evaluation: Uniform spherical particles, no agglomerates, no fines
Extractable matter (water): ≤ 0.03 %
Ce content: ≤ 1 µg/g
Pressure drop(column: ID=1.6 cm, L=10 cm at 5 ml/min): ≤ 5.0 bar
Particle size (d10): 20 - 28 µm
Particle size (d50): 24 - 34 µm
Particle size (d90): 28 - 38 µm
Colony forming units (TAMC + TYMC): ≤ 100 CFU/ml
Endotoxins: ≤ 1.00 EU/ml
Protein binding capacity (bovine serum albumin): 80 - 120 mg/ml
Functional test (b:a): ≤ 0.1
Functional Test: Seperation of conalbumin and human serum albumin

Informations légales

FRACTOGEL is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS02
• Mention d'avertissement: Warning
• Mentions de danger: H226
• Conseils de prudence: P210 - P233 - P240 - P241 - P242 - P243
• Classification des risques: Flam. Liq. 3
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 95.0 °F
• Point d'éclair (°C): 35 °C