P-917

Acetaminophen-D₄ solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Formule empirique (notation de Hill): C₈D₄H₅NO₂
• Numéro CAS: 64315-36-2
• Poids moléculaire : 155.19
• Numéro CE : 200-659-6
• Code UNSPSC : 41116107
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: certified reference material
• Forme: liquid
• Caractéristiques: Snap-N-Spike^®/Snap-N-Shoot^®
• Conditionnement: ampule of 1 mL
• Fabricant/nom de marque: Cerilliant^®
• Concentration: 1.0 mg/mL in methanol
• Technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Application(s): forensics and toxicology
• Format: single component solution
• Température de stockage: 2-8°C
• Chaîne SMILES: [2H]c1c([2H])c(NC(C)=O)c([2H])c([2H])c1O
• InChI: 1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)/i2D,3D,4D,5D
• Clé InChI: RZVAJINKPMORJF-QFFDRWTDSA-N

Description

Description générale

A stable-labeled internal standard suitable for quantitation of acetaminophen levels in urine, serum, or plasma by LC/MS or GC/MS for clinical toxicology, isotope dilution methods, P450 studies, and other pharmaceutical research. Acetaminophen, or Paracetamol, is a common over-the-counter COX inhibitor drug used for pain relief and fever reduction.

Application

• Simultaneous determination of acetaminophen and oxycoDonein human plasma by LC-MS/MS and its application to a pharmacokinetic study: This research demonstrates the application of Acetaminophen-D4 as an internal standard in the simultaneous analysis of acetaminophen and oxycoDoneusing LC-MS/MS. The study provides critical insights into drug metabolism and pharmacokinetic profiling, offering a reliable method for therapeutic monitoring and drug interaction studies in clinical pharmacology (Lu et al., 2018).

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS02,GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H225,H301 + H311 + H331,H370
• Conseils de prudence: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Classification des risques: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Organes cibles: Eyes
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 49.5 °F - closed cup
• Point d'éclair (°C): 9.7 °C - closed cup