878110C

C16-02:0 PC

Avanti Research^™ - A Croda Brand 878110C

• Synonyme(s) : 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine
• Formule empirique (notation de Hill): C₂₆H₅₄NO₇P
• Numéro CAS: 74389-68-7
• Poids moléculaire : 523.68
• Code UNSPSC : 12352211
• Nomenclature NACRES : NA.25

Propriétés

• Forme: liquid
• Conditionnement: pkg of 1 × 1 mL (878110C-5mg); pkg of 1 × 2.5 mL (878110C-25mg)
• Fabricant/nom de marque: Avanti Research^™ - A Croda Brand 878110C
• Concentration: 10 mg/mL (878110C-25mg); 5 mg/mL (878110C-5mg)
• Type de lipide: bioactive lipids; phosphoglycerides
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(C)=O)COCCCCCCCCCCCCCCCC)=O
• InChI: 1S/C26H54NO7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-31-23-26(34-25(2)28)24-33-35(29,30)32-22-20-27(3,4)5/h26H,6-24H2,1-5H3/t26-/m1/s1
• Clé InChI: HVAUUPRFYPCOCA-AREMUKBSSA-N

Description

Description générale

C16-02:0 PC, also known as 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine (C16 PAF) (acetyl PAF), is a platelet-activating factor (PAF). Acetyl PAF is present in the body and it contains ether-linked hexadecyl chain at the sn-1 position and an acetyl group at the sn-2 position.

Application

C16-02:0 PC or 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine, a platelet-activating factor (PAF) is used as a substrate for the determination of platelet-activating factor-acetylhydrolase (PAF-AH) activity in plasma or serum.

Actions biochimiques/physiologiques

Platelet-activating factor (PAF) is a pro-inflammatory agent that exhibits variety of biological and pharmacological effects. It plays a major role in initiation and progression of atherosclerosis. PAF acts as a potential biomarker for coronary artery diseases. It yields LysoPAF (1-O-alkyl-2-hydroxy-sn-glycero-3-phosphocholine) on hydrolysis by platelet-activating factor-acetylhydrolase.

Conditionnement

5 mL Clear Glass Sealed Ampule (878110C-25mg)

5 mL Clear Glass Sealed Ampule (878110C-5mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H302,H315,H319,H331,H336,H351,H361d,H372
• Conseils de prudence: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Classification des risques: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Organes cibles: Liver,Kidney, Respiratory system
• Code de la classe de stockage: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): does not flash
• Point d'éclair (°C): does not flash