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850475C

Avanti

18:1-16:0 PC

1-oleoyl-2-palmitoyl-sn-glycero-3-phosphocholine, chloroform

Synonyme(s) :

1--(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine; OPPC; PC(18:1(9Z)/16:0)

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About This Item

Formule empirique (notation de Hill):
C42H82NO8P
Numéro CAS:
59491-62-2
Poids moléculaire :
760.08
Code UNSPSC :
51191904
Nomenclature NACRES :
NA.25

Pureté

>99% (TLC)

Forme

liquid

Conditionnement

pkg of 1 × 2.5 mL (850475C-25mg)
pkg of 2 × 4 mL (850475C-200mg)

Fabricant/nom de marque

Avanti Research™ - A Croda Brand 850475C

Concentration

10 mg/mL (850475C-25mg)
25 mg/mL (850475C-200mg)

Type de lipide

cardiolipins
phospholipids

Conditions d'expédition

dry ice

Température de stockage

−20°C

InChI

1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-24-26-28-30-32-34-41(44)48-38-40(39-50-52(46,47)49-37-36-43(3,4)5)51-42(45)35-33-31-29-27-25-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1

Clé InChI

RRVPPYNAZJRZFR-VYOBOKEXSA-N

Description générale

Phosphatidylcholines (PCs) are mainly located on the outer leaflets of the biological membrane bilayer.

Application

18:1-16:0 PC (1-oleoyl-2-palmitoyl-sn-glycero-3-phosphocholine) may be used:
  • as a lipid standard in ultra-performance liquid chromatography (UPLC) analyses
  • as a component in liposomes to study the cell proliferation of several cell lines
  • in liposomes for cross-linking experiment

Actions biochimiques/physiologiques

Phosphatidylcholine (PC) serves as a major source for eicosanoids.

Conditionnement

5 mL Clear Glass Sealed Ampule (850475C-200mg)
5 mL Clear Glass Sealed Ampule (850475C-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogrammes

Skull and crossbonesHealth hazard
GHS06,GHS08

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Organes cibles

Liver,Kidney, Respiratory system

Code de la classe de stockage

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

does not flash

Point d'éclair (°C)

does not flash

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Anna Werlein et al.
Biochimica et biophysica acta, 1848(7), 1599-1608 (2015-04-29)
According to early experiments with natural extracts, phosphatidylcholines (PCs) are widely considered essentially non-toxic. In addition to these physiological mixed-chain PCs, many different synthetic diacyl-PCs are currently available, but they have never been systematically evaluated for any interference with cell
Eun A Ra et al.
Nature communications, 7, 11726-11726 (2016-05-25)
Autophagy is responsible for the bulk degradation of cytosolic constituents and plays an essential role in the intestinal epithelium by controlling beneficial host-bacterial relationships. Atg5 and Atg7 are thought to be critical for autophagy. However, Atg5- or Atg7-deficient cells still
Katharina Wozny et al.
Analytical and bioanalytical chemistry, 411(4), 915-924 (2018-12-24)
Diacyl glycerophospholipids (GPs) belong to the most abundant lipid species in living organisms and consist of a glycerol backbone with fatty acyl groups in sn-1 and sn-2 and a polar head group in the sn-3 position. Regioisomeric mixed diacyl GPs
Wei He et al.
Nanomedicine : nanotechnology, biology, and medicine, 24, 102154-102154 (2020-01-27)
In vivo delivery of large RNA molecules has significant implications for novel gene therapy, biologics delivery, and vaccine applications. We have developed cationic nanolipoprotein particles (NLPs) to enhance the complexation and delivery of large self-amplifying mRNAs (replicons) in vivo. NLPs
Jone Garate et al.
Journal of the American Society for Mass Spectrometry, 31(3), 517-526 (2020-03-05)
Imaging mass spectrometry (IMS) is becoming an essential technique in lipidomics. Still, many questions remain open, precluding it from achieving its full potential. Among them, identification of species directly from the tissue is of paramount importance. However, it is not
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