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850397C

Avanti

20:4 (Cis) PC

1,2-diarachidonoyl-sn-glycero-3-phosphocholine, chloroform

Synonyme(s) :

1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine; DAPC; PC(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z))

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About This Item

Formule empirique (notation de Hill):
C48H80NO8P
Numéro CAS:
Poids moléculaire :
830.12
Code UNSPSC :
51191904
Nomenclature NACRES :
NA.25

Pureté

>99% (TLC)

Forme

liquid

Conditionnement

pkg of 1 × 2.5 mL (850397C-25mg)
pkg of 2 × 4 mL (850397C-200mg)

Fabricant/nom de marque

Avanti Research - A Croda Brand 850397C

Concentration

10 mg/mL (850397C-25mg)
25 mg/mL (850397C-200mg)

Type de lipide

cardiolipins
phospholipids

Conditions d'expédition

dry ice

Température de stockage

−20°C

InChI

1S/C48H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-47(50)54-44-46(45-56-58(52,53)55-43-42-49(3,4)5)57-48(51)41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h14-17,20-23,26-29,32-35,46H,6-13,18-19,24-25,30-31,36-45H2,1-5H3/b16-14-,17-15+,22-20-,23-21-,28-26-,29-27-,34-32-,35-33-/t46-/m1/s1

Clé InChI

LZLVZIFMYXDKCN-HLKGGLNDSA-N

Description générale

20:4 (cis) PC or 1,2-diarachidonoyl-sn-glycero-3-phosphocholine is an unsaturated glycerophospholipid, with substitution of two chains of arachidonic acid at sn-1 and sn-2 positions of the glycerol backbone, along with choline as a headgroup.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

20:4 (cis) PC or 1,2-diarachidonoyl-sn-glycero-3-phosphocholine might be used:
  • in lipid bilayer, to study its effect on membrane vesiculation by dynamin and endophilin
  • as a phosphatidylcholine (PC) standard to compare the extraction efficiency of the three tested solvent systems prior to liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) analysis
  • in low density lipid (LDL)-mimicking liposome as an alternative to LDL for evaluating the LDL-oxidation preventing antioxidants

Conditionnement

5 mL Clear Glass Sealed Ampule (850397C-200mg)
5 mL Clear Glass Sealed Ampule (850397C-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogrammes

Skull and crossbonesHealth hazard

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Organes cibles

Liver,Kidney, Respiratory system

Code de la classe de stockage

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

does not flash

Point d'éclair (°C)

does not flash


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Ana Gonzálvez et al.
Analytical and bioanalytical chemistry, 396(8), 2965-2975 (2010-02-27)
A zirconia (ZrO(2))-modified solid-phase extraction sorbent has been evaluated for selective extraction of phosphatidylcholines from biological samples, followed by analysis of the isolated solutes by reversed-phase liquid chromatography-electrospray ionization-tandem mass spectrometry. The clean-up process was optimized using seven standard phosphatidylcholines
Seiji Takeda et al.
Biochemical and biophysical research communications, 513(1), 275-279 (2019-04-08)
Oxidation of low-density lipoproteins (LDL) causes atherosclerosis. Detection of oxidation of LDL-mimetic liposomes using an electrode might serve as a convenient tool in the search of antioxidants for the prevention of atherosclerosis. This report proposes a reaction mechanism between LDL-mimetic
Marco M Manni et al.
eLife, 7 (2018-03-16)
Phospholipid membranes form cellular barriers but need to be flexible enough to divide by fission. Phospholipids generally contain a saturated fatty acid (FA) at position sn1 whereas the sn2-FA is saturated, monounsaturated or polyunsaturated. Our understanding of the impact of

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