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Key Documents

791281P

Avanti

α-mycolic acid, methoxy cis

powder

Synonyme(s) :

Cyclopropaneeicosanoic acid, β-hydroxy-2-[(17S,18S)-17-methoxy-18-methylhexatriacontyl]-α-tetracosyl-, (αR,βR,1R,2S)-

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About This Item

Formule empirique (notation de Hill):
C85H168O4
Numéro CAS:
23599-54-4
Poids moléculaire :
1254.24
Code UNSPSC :
12352211
Nomenclature NACRES :
NA.25

Forme

powder

Conditionnement

pkg of 1 × 1 mg (791281P-1mg)

Fabricant/nom de marque

Avanti Research™ - A Croda Brand 791281P

Type de lipide

bacterial lipids

Conditions d'expédition

dry ice

Température de stockage

−20°C

Description générale

α-mycolic acid (MA), methoxy cis comprises 84–88 carbon atoms like the other types keto and hydroxy MA. All the MA types are synthesized from hydroxylated intermediate, with methoxy M generated by the action of enzyme methoxylase.
Mycolic acid is a long Fatty acid found in the cell walls of the mycolata taxon, a group of bacteria that includes Mycobacterium tuberculosis, the causative agent of the disease tuberculosis.

Actions biochimiques/physiologiques

Methoxy mycolic acids are antigenic and are specific for pathogenic mycobacterial class. The three types of mycolic acids including the methoxy-MA display variation in their antigenicity with reference to antibody recognition.

Conditionnement

5 mL Amber Glass Screw Cap Vial (791281P-1mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Code de la classe de stockage

11 - Combustible Solids

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Consulter la Bibliothèque de documents

Hedia Marrakchi et al.
Chemistry & biology, 21(1), 67-85 (2014-01-01)
Mycolic acids are major and specific lipid components of the mycobacterial cell envelope and are essential for the survival of members of the genus Mycobacterium that contains the causative agents of both tuberculosis and leprosy. In the alarming context of
Nabil Tahiri et al.
Angewandte Chemie (International ed. in English), 59(19), 7555-7560 (2020-02-19)
In Mycobacterium tuberculosis, mycolic acids and their glycerol, glucose, and trehalose esters ("cord factor") form the main part of the mycomembrane. Despite their first isolation almost a century ago, full stereochemical evaluation is lacking, as is a scalable synthesis required
Heena Ranchod et al.
PloS one, 13(8), e0200298-e0200298 (2018-08-10)
Mycolic acids (MA) are major, species-specific lipid components of Mycobacteria and related genera. In Mycobacterium tuberculosis, it is made up of alpha-, methoxy- and keto-MA, each with specific biological functions and conformational characteristics. Antibodies in tuberculosis (TB) patient sera respond

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