790404P
Avanti
18:1 DGS-NTA(Ni)
Avanti Research™ - A Croda Brand
Synonyme(s) :
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (nickel salt); DOGS NTA
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About This Item
Formule empirique (notation de Hill):
C53H93N2O15Ni
Numéro CAS:
Poids moléculaire :
1057.00
Code UNSPSC :
12352211
Nomenclature NACRES :
NA.25
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Description
1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (nickel salt)
Pureté
>99% (TLC)
Forme
powder
Conditionnement
pkg of 1 × 10 mg (790404P-10mg)
pkg of 1 × 25 mg (790404P-25mg)
pkg of 1 × 5 mg (790404P-5mg)
Fabricant/nom de marque
Avanti Research™ - A Croda Brand
Conditions d'expédition
dry ice
Température de stockage
−20°C
Catégories apparentées
Description générale
1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] nitrilotriacetic acid (NTA) (18:1 DGS-NTA(Ni)) is a conjugated phospholipid that contains nickel. NTA chelates with four of the six coordination sites present in nickel ion.
Application
1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] (nickel salt) (18:1 DGS-NTA(Ni)) has been used:
- in the preparation of liposomes with porphyrin-phospholipid (PoP) conjugate for protein and peptide binding studies
- in the preparation of nanosize multillamelar vesicles (NMVs) for antigen delivery studies
- as a component of small unilamellar vesicle (SUV) for planar lipid membrane (PM) preparation
Actions biochimiques/physiologiques
1,2-dioleoyl-sn-glycero-3-[(N-(5-amino-1-carboxypentyl)iminodiacetic acid)succinyl] nitrilotriacetic acid (NTA) (18:1 DGS-NTA(Ni)) is useful in structural biology especially to bind recombinant histidine tagged proteins. Though useful, being nanoparticulate it has stability problems in biological samples. So NTA-lipid conjugate is majorly used as liposomes or as a coating to nanoparticle. DGS-NTA (Ni) based nanosize multillamelar vesicles (NMVs) are potent vaccine delivery system.
Conditionnement
5 mL Clear Glass Sealed Ampule (790404P-10mg)
5 mL Clear Glass Sealed Ampule (790404P-25mg)
5 mL Clear Glass Sealed Ampule (790404P-5mg)
Informations légales
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Souvent commandé avec ce produit
Code de la classe de stockage
11 - Combustible Solids
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