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Key Documents

921963

Sigma-Aldrich

Droplet generator chip - Multi channel design

Fluidic 285, PC

Synonyme(s) :

Microfluidic chip

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About This Item

Code UNSPSC :
42142600
Nomenclature NACRES :
NA.23

Description

Microfludic chip x1

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Application

Microfluidic generation of droplets can produce highly monodispersed droplets with high frequency (up to hundreds of kHz). Interest in droplet-based microfluidic systems has grown substantially, because microfluidics offers the ability to handle very small volumes (μl to fl) of reagents, provides better mixing, encapsulation, sorting, and sensing. Microfluidics can be used for high throughput experimentation. Microfluidic-based droplets have many diverse and varied applications such as particle synthesis and chemical analysis. Highly controlled droplet production also makes single cell analysis, or drug testing possible.

Droplet generator chip - Multi channel design, Fluidic 285, PC is made of PC (polycarbonate), and has various droplet generation units. The chip features five different droplet generation units with multiple channel designs and sizes, enabling a large set of experiments. Channels/ports not in use can easily be closed by means of Mini Luer plugs. With this multichannel design several design options to generate droplets with different volumes are implemented. Main channel as well as entrance channel vary in diameter enabling a large set of experiments. Fluidic 285 features Mini Luer interfaces.

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Recent advances of controlled drug delivery usingmicrofluidic platforms.
Li X, et al.
Advanced Drug Delivery Reviews, 128, 3-28 (2018)
Microfluidic-assisted fabrication of carriers for controlled drug delivery.
Santos H A, et al.
Lab on a chip, 17, 1856-1883 (2017)
Dongfei Liu et al.
Lab on a chip, 17(11), 1856-1883 (2017-05-10)
The microfluidic technique has brought unique opportunities toward the full control over the production processes for drug delivery carriers, owing to the miniaturisation of the fluidic environment. In comparison to the conventional batch methods, the microfluidic setup provides a range
Sharma T Sanjay et al.
Advanced drug delivery reviews, 128, 3-28 (2017-09-19)
Conventional systematically-administered drugs distribute evenly throughout the body, get degraded and excreted rapidly while crossing many biological barriers, leaving minimum amounts of the drugs at pathological sites. Controlled drug delivery aims to deliver drugs to the target sites at desired

Articles

Microfluidic assembly improves polyamine nanoencapsulation of nucleic acids, overcoming challenges like polydispersity and poor reproducibility.

Microfluidic assembly improves polyamine nanoencapsulation of nucleic acids, overcoming challenges like polydispersity and poor reproducibility.

Microfluidic assembly improves polyamine nanoencapsulation of nucleic acids, overcoming challenges like polydispersity and poor reproducibility.

Microfluidic assembly improves polyamine nanoencapsulation of nucleic acids, overcoming challenges like polydispersity and poor reproducibility.

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