902381
Maleimide-poly(ethylene glycol)-b-poly(ε-caprolactone)
PEG average Mn 5000, PCL average Mn 5000
Synonyme(s) :
PEG-b-PCL, PEG-PCL
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About This Item
Formule linéaire :
C9H12O3NS[C2H4O]n[C6H10O2]mH
Code UNSPSC :
12352005
Nomenclature NACRES :
NA.23
Produits recommandés
Forme
powder or solid
Poids mol.
PCL average Mn 5000
PEG average Mn 5000
Couleur
white to off-white
PDI
≤1.3 (by GPC)
Température de stockage
−20°C
Catégories apparentées
Application
Maleimide-poly(ethylene glycol)-b-poly(ε-caprolactone) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PCL block.These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). Additionally, well-defined nanoparticles with tunable size and properties can be prepared by altering the molecular weight ratios between hydrophilic and hydrophobic blocks, as well as by controlling formulation parameters. The carboxylic acid functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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Les clients ont également consulté
Jian Jin et al.
PloS one, 9(11), e112200-e112200 (2014-11-12)
In this content, a small molecular ligand of prostate specific membrane antigen (SMLP) conjugated poly (caprolactone) (PCL)-b-poly (ethylene glycol) (PEG) copolymers with different block lengths were synthesized to construct a satisfactory drug delivery system. Four different docetaxel-loaded polymeric micelles (DTX-PMs)
Cem Varan et al.
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