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776025

Sigma-Aldrich

Maleimidolinourea-Rh110-trimethyl lock

95%

Synonyme(s) :

Maleimidourea-rhodamine-110 trimethyl lock

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About This Item

Formule empirique (notation de Hill):
C43H40N4O9
Numéro CAS:
Poids moléculaire :
756.80
Code UNSPSC :
12352202
ID de substance PubChem :
Nomenclature NACRES :
NA.22

Pureté

95%

Forme

powder

Température de stockage

−20°C

Chaîne SMILES 

O=C(O1)C2=CC=CC=C2C31C(C=CC(NC(NCCCN4C(C=CC4=O)=O)=O)=C5)=C5OC6=C3C=CC(NC(CC(C)(C)C7=C(OC(C)=O)C=C(C)C=C7C)=O)=C6

InChI

1S/C43H40N4O9/c1-24-19-25(2)39(35(20-24)54-26(3)48)42(4,5)23-36(49)45-27-11-13-31-33(21-27)55-34-22-28(46-41(53)44-17-8-18-47-37(50)15-16-38(47)51)12-14-32(34)43(31)30-10-7-6-9-29(30)40(52)56-43/h6-7,9-16,19-22H,8,17-18,23H2,1-5H3,(H,45,49)(H2,44,46,53)

Clé InChI

XMGVLBGRSCGJDI-UHFFFAOYSA-N

Catégories apparentées

Application

Maleimidourea-rhodamine-110 trimethyl lock may be used:
  • Rhodamine 110 based pro-fluorophore activated by esterases in cells.
  • Maleimide functionalized for conjugation to thiolates of small molecules or biomolecules.
  • High signal to noise ratio compared to fluorescein diacetate.
  • Able to fluorescently monitor passage of biomolecules into cells.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Consulter la Bibliothèque de documents

Luke D Lavis et al.
ACS chemical biology, 1(4), 252-260 (2006-12-14)
Traditional small-molecule fluorophores are always fluorescent. This attribute can obscure valuable information in biological experiments. Here, we report on a versatile "latent" fluorophore that overcomes this limitation. At the core of the latent fluorophore is a derivative of rhodamine in
Sunil S Chandran et al.
Journal of the American Chemical Society, 127(6), 1652-1653 (2005-02-11)
Fluorescent molecules are essential for basic research in the biological sciences and have numerous practical applications. Herein is described the synthesis and use of a new class of latent fluorophores based on a novel design element, the trimethyl lock, that

Contenu apparenté

Professor Ron Raines works with Sigma-Aldrich on the development of reagents and tools for chemical biology such as the traceless Staudinger ligation reagent (670359). DTBA (774405), a superior biological reducing reagent to DTT, is another technology to come out of the Raines lab.

Professor Ron Raines works with Sigma-Aldrich on the development of reagents and tools for chemical biology such as the traceless Staudinger ligation reagent (670359). DTBA (774405), a superior biological reducing reagent to DTT, is another technology to come out of the Raines lab.

Professor Ron Raines works with Sigma-Aldrich on the development of reagents and tools for chemical biology such as the traceless Staudinger ligation reagent (670359). DTBA (774405), a superior biological reducing reagent to DTT, is another technology to come out of the Raines lab.

Professor Ron Raines works with Sigma-Aldrich on the development of reagents and tools for chemical biology such as the traceless Staudinger ligation reagent (670359). DTBA (774405), a superior biological reducing reagent to DTT, is another technology to come out of the Raines lab.

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

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