663190

Ethyl 5-methylindole-2-carboxylate

97%

• Synonyme(s) : 5-Methylindole-2-carboxylic acid ethyl ester, NSC 30928
• Formule empirique (notation de Hill): C₁₂H₁₃NO₂
• Numéro CAS: 16382-15-3
• Poids moléculaire : 203.24
• Numéro MDL: MFCD00022703
• Code UNSPSC : 12352100
• ID de substance PubChem : 24884618
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 100
• Pureté: 97%
• Forme: solid
• Pf: 160-164 °C
• Chaîne SMILES: CCOC(=O)c1cc2cc(C)ccc2[nH]1
• InChI: 1S/C12H13NO2/c1-3-15-12(14)11-7-9-6-8(2)4-5-10(9)13-11/h4-7,13H,3H2,1-2H3
• Clé InChI: KMVFKXFOPNKHEM-UHFFFAOYSA-N

Description

Description générale

Ethyl 5-methylindole-2-carboxylate (5-Methylindole-2-carboxylic acid ethyl ester) is an indole derivative. Indole ring system is an important building block or intermediate in the synthesis of many pharmaceutical agents. It is formed during the Fischer indolization of ethyl pyruvate 2-[2-(methanesulfonyloxy)-4-methyl]phenylhydrazine.

Application

• Reactant for synthesis of oxazino[4,3-a]indoles via cascade addition-cyclization reactions
• Reactant for preparation of indolecarboxamides as cannabinoid CB1 receptor antagonists
• Reactant for preparation of indole-3-propionic acids as antiinflammatory and analgesic agents
• Reactant for Friedel-Crafts acylation with nitrobenzoyl chloride
• Reactant for oximation reactions

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)