320129

Acetyl chloride

reagent grade, 98%

• Synonyme(s) : Acetic acid chloride, Acetic chloride, Ethanoyl chloride
• Formule linéaire : CH₃COCl
• Numéro CAS: 75-36-5
• Poids moléculaire : 78.50
• Beilstein: 605303
• Numéro CE : 200-865-6
• Numéro MDL: MFCD00000719
• Code UNSPSC : 12352100
• ID de substance PubChem : 24859250
• Nomenclature NACRES : NA.22

Propriétés

• Qualité: reagent grade
• Densité de vapeur: 2.7 (vs air)
• Pression de vapeur: 11.69 psi ( 20 °C); 32.33 psi ( 55 °C)
• Essai: 98%
• Forme: liquid
• Température d'inflammation spontanée: 1353 °F
• Limite d'explosivité: 19 %
• Indice de réfraction: n20/D 1.389 (lit.)
• pb: 52 °C (lit.)
• Pf: −112 °C (lit.)
• Densité: 1.104 g/mL at 25 °C (lit.)
• Groupe fonctionnel: acyl chloride
• Chaîne SMILES: CC(Cl)=O
• InChI: 1S/C2H3ClO/c1-2(3)4/h1H3
• Clé InChI: WETWJCDKMRHUPV-UHFFFAOYSA-N

Description

Description générale

Acetyl chloride undergoes reaction with decalin and aluminum trichloride to afford a tricyclic enol ether. It promotes the cyclopropanation of alkene with dibromomethane or diiodomethane in the presence of Zn dust and copper chloride in ether. Friedel-Crafts reaction of acetyl chloride with benzene in the presence of MCl₃ (M = Al or Fe) in the ionic liquid 1-butyl-3-methylimidazolium chloride affords MCl₃ adducts of the acetyl chloride, the acetylium ion [CH₃CO]⁺[MCl₄]^- and the MCl₃ adduct of acetophenone.

Application

• Synthesis, Characterization, and Evaluation of Thiazolidine Derivatives of Cysteine for Suppressing Eumelanin Production.: The study discusses the synthesis and evaluation of thiazolidine derivatives of cysteine, where acetyl chloride is used as a reagent, underscoring its importance in pharmaceutical intermediate development. (Amino et al., 2016).
• New URJC-1 Material with Remarkable Stability and Acid-Base Catalytic Properties.: This research introduces the new URJC-1 material, noting its stability and catalytic properties, with acetyl chloride being pivotal in the synthesis process, illustrating its role in material science and catalysis. (Leo et al., 2016).

Informations sur la sécurité

• Pictogrammes: GHS02,GHS05
• Mention d'avertissement: Danger
• Mentions de danger: H225,H314
• Conseils de prudence: P210 - P233 - P240 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Classification des risques: Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B
• Risques supp: EUH014
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 41.0 °F - closed cup
• Point d'éclair (°C): 5 °C - closed cup