Skip to Content
Merck
All Photos(3)

Key Documents

View All Documentation

SML3767

Sigma-Aldrich

AA-263

≥98% (HPLC)

Synonym(s):

2-Hydroxybenzaldehyde 2-(4-nitrophenyl)hydrazone, NSC 101540, Salicylaldehyde 4-nitrophenylhydrazone, o-Hydroxybenzaldehyde p-nitrophenylhydrazone

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

Empirical Formula (Hill Notation):
C13H11N3O3
CAS Number:
3155-24-6
Molecular Weight:
257.24
MDL number:
MFCD00425292
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

, Faint orange to Red

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

Biochem/physiol Actions

AA-263 is a cell penetrant, potent and selective ATF6 activator that corrects the trafficking, conformation, secretion, and function of AAT-Z. AA-263 increases AAT neutrophil elastase (NE) inhibitory activity, while reducing polymer accumulation for the majority of AATD (alpha-1 antitrypsin (AAT) causes AAT deficiency) variants.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Capturing the conversion of the pathogenic alpha-1-antitrypsin fold by ATF6 enhanced proteostasis
Cell Chemical Biology, 30(1) (2023)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service