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N6875

Sigma-Aldrich

2-Naphthyl acetate

Synonym(s):

β-Naphthyl acetate

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About This Item

Linear Formula:
CH3CO2C10H7
CAS Number:
1523-11-1
Molecular Weight:
186.21
Beilstein:
1868291
EC Number:
216-194-7
MDL number:
MFCD00004060
UNSPSC Code:
12352204
PubChem Substance ID:
24897794
NACRES:
NA.32

form

powder

Quality Level

100

impurities

<0.2% Free naphthol

mp

67-70 °C (lit.)

solubility

ethanol: 50 mg/mL

storage temp.

−20°C

SMILES string

CC(=O)Oc1ccc2ccccc2c1

InChI

1S/C12H10O2/c1-9(13)14-12-7-6-10-4-2-3-5-11(10)8-12/h2-8H,1H3

InChI key

RJNPPEUAJCEUPV-UHFFFAOYSA-N

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Application

2-Naphthyl acetate has been used as a substrate:
  • in substrate sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) to examine the composition of lipases in larvae and adult specimens
  • in the preparation of zymograms to identify proteins with lipase activity
  • to measure non-specific esterase activity and β-esterase enzyme activity

Biochem/physiol Actions

2-Naphthyl acetate/β-naphthyl acetate (BNA) is an ester substrate. It can be used in staining gels to detect esterase activity. BNA dissolved in acetone and ethanol produces a dark and very light/no background respectively. Hence destaining is not necessary if ethanol is used to dissolve BNA for esterase staining of gels.

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H318

Precautionary Statements

P280 - P305 + P351 + P338

Hazard Classifications

Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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