D9641

Deoxygalactonojirimycin hydrochloride

powder or solid, ≥98% (HPLC)

• Synonym(s): 1,5-Dideoxy-1,5-imino-D-galactitol, Migalastat
• Empirical Formula (Hill Notation): C₆H₁₃NO₄ · HCl
• CAS Number: 75172-81-5
• Molecular Weight: 199.63
• UNSPSC Code: 12352200
• PubChem Substance ID: 329798908
• NACRES: NA.32
• MDL number: MFCD00269962

Properties

• Product Name: Deoxygalactonojirimycin hydrochloride,
• biological source: synthetic (organic)
• assay: ≥98% (HPLC)
• form: powder or solid
• solubility: water: soluble 1 mg/mL
• storage temp.: −20°C
• SMILES string: Cl.OC[C@H]1NC[C@H](O)[C@@H](O)[C@H]1O
• InChI: 1S/C6H13NO4.ClH/c8-2-3-5(10)6(11)4(9)1-7-3;/h3-11H,1-2H2;1H/t3-,4+,5+,6-;/m1./s1
• InChI key: ZJIHMALTJRDNQI-OLALXQGDSA-N

Description

Application

Deoxygalactonojirimycin hydrochloride has been used as an α-galactosidase A inhibitor to assess the enzymatic activity of α-galactosidase A. It has also been used as an α-galactosidase A inhibitor to study its effects on the mRNA levels in human embryonic kidney (HEK) cells and hippocampal neurons.

Biochem/physiol Actions

Deoxygalactonojirimycin hydrochloride is an inhibitor of α-galactosidase A. Deoxygalactonojirimycin exhibits therapeutic effects against Fabry disease.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Gloves