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N5000

Sigma-Aldrich

Naphthol AS-MX phosphate disodium salt

≥98% purity (HPLC), powder

Synonym(s):

Naphthol AS-MX phosphate disodium salt, phosphatase substratesodium 3-(2,4-dimethylphenylcarbamoyl)naphthalen-2-yl phosphate

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About This Item

Linear Formula:
C19H16NO5PNa2
CAS Number:
Molecular Weight:
415.29
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

product name

Naphthol AS-MX phosphate disodium salt, phosphatase substrate

Quality Level

Assay

≥98.0% (HPLC)

form

powder

solubility

water: 100 mg/mL, clear to hazy

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

SMILES string

[Na+].[Na+].Cc1ccc(NC(=O)c2cc3ccccc3cc2OP([O-])([O-])=O)c(C)c1

InChI

1S/C19H18NO5P.2Na/c1-12-7-8-17(13(2)9-12)20-19(21)16-10-14-5-3-4-6-15(14)11-18(16)25-26(22,23)24;;/h3-11H,1-2H3,(H,20,21)(H2,22,23,24);;/q;2*+1/p-2

InChI key

IHRJBGLDOBEMPR-UHFFFAOYSA-L

Application

Naphthol AS-MX phosphate disodium salt is intended for use as a substrate for the histochemical demonstration of alkaline phosphatase activities.

Substrates

Substrate for the histochemical demonstration of acid and alkaline phosphatase.

related product

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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D M Boorsma
Histochemistry, 80(2), 103-106 (1984-01-01)
A novel method for immunoenzymatic double staining was developed, using primary antibodies directly labeled with either horseradish peroxidase or alkaline phosphatase. The enzyme-antibody conjugates were applied simultaneously on sections of human tonsil. Intracytoplasmic antigens like immunoglobulins and light chains could
CYTOCHEMICAL DEMONSTRATION OF ACID PHOSPHATASE IN HEMATOPOIETIC CELLS IN HEALTH AND IN VARIOUS HEMATOLOGICAL DISORDERS USING AZO DYE TECHNIQUES.
L S KAPLOW et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 12, 805-811 (1964-11-01)
Lars Gläser et al.
Microbial cell factories, 19(1), 160-160 (2020-08-12)
Thioesters of coenzyme A participate in 5% of all enzymatic reactions. In microbial cell factories, they function as building blocks for products of recognized commercial value, including natural products such as polyketides, polyunsaturated fatty acids, biofuels, and biopolymers. A core
Maintenance and neuronal differentiation of chicken induced pluripotent stem-like cells.
Dai R
Stem Cells International, 2014, 182737-182737 (2014)
S J Harper et al.
Journal of clinical pathology, 45(2), 114-119 (1992-02-01)
The development of a technique for simultaneous in situ hybridisation for native mRNA and conventional immunofluorescence for cytoplasmic antigens in routine pathology specimens. Cocktails of synthetic deoxyoligonucleotides coding for immunoglobulin J chain and kappa light chain were 3' end labelled

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