AB1555
Anti-NMDAR2A Antibody
serum, Chemicon®
Synonym(s):
Anti-EPND, Anti-GluN2A, Anti-LKS, Anti-NMDAR2A, Anti-NR2A
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
fish, human, rat, mouse
manufacturer/tradename
Chemicon®
technique(s)
immunoprecipitation (IP): suitable
western blot: suitable
suitability
not suitable for immunohistochemistry
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... GRIN2A(2903)
Specificity
NMDAR2A. By Western blot it recognizes a 180 kDa band in rat brain membranes.
Immunogen
C-Terminal Fusion Protein of the NMDAR2A (30 kDa), aa 1253-1391.
Application
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neurotransmitters & Receptors
This Anti-NMDAR2A Antibody is validated for use in IP, WB for the detection of NMDAR2A.
Western blotting*: 1:1,000-1:5,000 for ECL. If using labled protein-A for detection: 1:200.
* See suggested protocol
Immunoprecipitation using solubilized hippocampal slices. 3μL will (under appropriate conditions) quantitatively immunoprecipitate all NMDAR2A in 200μg rat brain.
Not suggested for use in immunohistochemistry.
Optimal working dilutions must be determined by the end user.
* See suggested protocol
Immunoprecipitation using solubilized hippocampal slices. 3μL will (under appropriate conditions) quantitatively immunoprecipitate all NMDAR2A in 200μg rat brain.
Not suggested for use in immunohistochemistry.
Optimal working dilutions must be determined by the end user.
Physical form
Rabbit antiserum. Liquid, no preservatives.
Storage and Stability
Maintain at -20°C in undiluted aliquots for up to one year. Avoid repeated freeze/thaw cycles.
Analysis Note
Control
NMDAR2A is present in high concentrations in the hippocampus
NMDAR2A is present in high concentrations in the hippocampus
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Description
Pricing
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Effects of repeated prenatal glucocorticoid exposure on long-term potentiation in the juvenile guinea-pig hippocampus.
Setiawan, E; Jackson, MF; MacDonald, JF; Matthews, SG
The Journal of Physiology null
Zhen-Zhen Duan et al.
Scientific reports, 6, 29246-29246 (2016-07-08)
It has been demonstrated that Src could modulate NMDA receptor, and PAR1 could also affect NMDAR signaling. However, whether PAR1 could regulate NMDAR through Src under ICH has not yet been investigated. In this study, we demonstrated the role of
Visual experience-independent functional expression of NMDA receptors in the developing rabbit retina.
Chang, YC; Chen, CY; Chiao, CC
Investigative Ophthalmology & Visual Science null
Annabelle Schlüter et al.
Molecular therapy. Methods & clinical development, 17, 281-299 (2020-02-15)
In the central nervous system, neurons and the vasculature influence each other. While it is well described that a functional vascular system is trophic to neurons and that vascular damage contributes to neurodegeneration, the opposite scenario in which neural damage
Sharon A Swanger et al.
American journal of human genetics, 99(6), 1261-1280 (2016-11-15)
Epilepsy and intellectual disability are associated with rare variants in the GluN2A and GluN2B (encoded by GRIN2A and GRIN2B) subunits of the N-methyl-D-aspartate receptor (NMDAR), a ligand-gated ion channel with essential roles in brain development and function. By assessing genetic
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