Skip to Content
Merck
All Photos(1)

Documents

W355690

Sigma-Aldrich

Isopropyl myristate

≥98%

Synonym(s):

Isopropyl tetradecanoate, Myristic acid isopropyl ester

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
CH3(CH2)12COOCH(CH3)2
CAS Number:
Molecular Weight:
270.45
FEMA Number:
3556
Beilstein:
1781127
EC Number:
Council of Europe no.:
386
MDL number:
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
9.105
NACRES:
NA.21

biological source

synthetic

Quality Level

grade

Fragrance grade
Halal
Kosher

Agency

follows IFRA guidelines

reg. compliance

EU Regulation 1223/2009

Assay

≥98%

refractive index

n20/D 1.434 (lit.)

bp

193 °C/20 mmHg (lit.)

mp

~3 °C (lit.)

density

0.85 g/mL at 25 °C (lit.)

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

no known allergens

fragrance allergen

no known allergens

Organoleptic

faint; fatty; oily

SMILES string

CCCCCCCCCCCCCC(=O)OC(C)C

InChI

1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3

InChI key

AXISYYRBXTVTFY-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Isopropyl myristate is mainly used as a solubilizer, emulsifier and emollient in cosmetic and topical medicines. It is also used as a flavoring agent in the food industry.

Application


  • Development of Nanostructured Lipid Carrier-Loaded Flavonoid-Enriched Zingiber officinale.: This research develops nanostructured lipid carriers for flavonoids derived from Zingiber officinale, employing Isopropyl myristate to stabilize these carriers and improve bioactive compound delivery (Shazwani SS et al., 2024).

  • Comparative evaluation of physical and chemical enhancement techniques for transdermal delivery of linagliptin.: The study compares various enhancement methods for transdermal drug delivery, including the use of Isopropyl myristate, highlighting its effectiveness in permeation enhancement techniques (Karve T et al., 2024).

  • Optimization of Conditions of Zanthoxylum Alkylamides Liposomes by Response Surface Methodology and the Absorption Characteristics of Liposomes in the Caco-2 Cell Monolayer Model.: This research optimizes liposome formulations containing Zanthoxylum alkylamides, with Isopropyl myristate being crucial in liposome stability and absorption characteristics (Wang R et al., 2024).

Biochem/physiol Actions

Odor at 1.0%
Taste at 10 ppm

Disclaimer

For R&D or non-EU Food use. Not for retail sale.

Storage Class Code

10 - Combustible liquids

WGK

awg

Flash Point(F)

>302.0 °F

Flash Point(C)

> 150 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Handbook of Preservatives, 425-425 (2004)
Ranajay Saha et al.
Langmuir : the ACS journal of surfaces and colloids, 28(22), 8309-8317 (2012-05-11)
An edible microemulsion (ME) composed of Tween 80/butyl lactate/isopropyl myristate (IPM)/water has been formulated. Pseudoternary phase diagram of the system contains a large single isotropic region. The phase behavior of the system is also studied at low pH (2.6) and
Fan Yang et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 82(1), 158-163 (2012-06-21)
Transdermal delivery of methotrexate (MTX) was investigated by using the solid-in-oil (S/O) technique. Because MTX was coated with nonionic surfactant molecules, the resulting complex was easy to dissolve in various organic solvents and provided a transparent solution in isopropyl myristate
Qian Zhang et al.
Pharmaceutical research, 30(1), 32-40 (2012-08-28)
In principle, maximum transepidermal fluxes of solutes should be similar for different vehicles, except when the solute or vehicle modifies the skin. Here we estimated maximum flux, stratum corneum solubility, diffusivity and permeability coefficient for a range of similarly sized
Ji Zhang et al.
International journal of pharmaceutics, 421(1), 34-44 (2011-10-01)
In this study, microemulsion microstructures, key formulation variables, and their relationship to drug transdermal permeation enhancement were investigated. A microemulsion system with high water soluble capacity was developed, using isopropyl myristate, Labrasol, and Cremophor EL as oil, surfactant, and co-surfactant

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service