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900148

Sigma-Aldrich

Iron oxide (II,III), nanoparticles

30 nm avg. part. size (TEM), streptavidin functionalized, 1 mg/mL in H2O

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About This Item

UNSPSC Code:
12352303
NACRES:
NA.23

form

dispersion
nanoparticles

Quality Level

100

packaging

pkg of 1 mL

storage condition

do not freeze

concentration

1 mg/mL in H2O

avg. part. size

30 nm (TEM)

functional group

streptavidin

storage temp.

2-8°C

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General description

Recent docking studies highlight the potential interaction of iron oxide (II,III) nanoparticles (IONPs) with the SARS-CoV-2 spike protein receptor binding domain. This may target viral entry in host cells and also render virions inactive.

Application

IONPs may be used in the nanoparticle preparation for evaluation of their antiviral property against H1N1 influenza A virus.
Iron oxide nanoparticles exhibit biocompatibility and non-toxicity and are used as magnetic resonance imaging contrast agents, gene carriers for gene therapy, therapeutic agents for hyperthermia-based cancer treatment, magnetic sensing probes for in vivo diagnostics and for target specific drug delivery.

Legal Information

Product of Ocean Nanotech, LLC.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCV7765
MKCW5546
MKCT4180
MKCS1024
MKCS1658

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A Molecular Docking Study Repurposes FDA Approved Iron Oxide Nanoparticles to Treat and Control COVID-19 Infection
Abo-Zeid Y, et al.
European Journal of Pharmaceutical Sciences, 105465-105465 (2020)
Iron oxide nanoparticles based antiviral activity of H1N1 influenza A virus
Kumar R, et al.
Journal of Infection and Chemotherapy, 25(5), 325-329 (2019)
Xianglong Hu et al.
Dalton transactions (Cambridge, England : 2003), 44(9), 3904-3922 (2015-01-13)
Responsive polymeric assemblies and hybrid superstructures fabricated from stimuli-sensitive polymers and inorganic nanoparticles (NPs) have been the subject of extensive investigations during the past few decades due to their distinct advantages such as an improved water solubility, stimuli-responsiveness, excellent biocompatibility
Joan Estelrich et al.
International journal of molecular sciences, 16(4), 8070-8101 (2015-04-14)
In this review, we discuss the recent advances in and problems with the use of magnetically-guided and magnetically-responsive nanoparticles in drug delivery and magnetofection. In magnetically-guided nanoparticles, a constant external magnetic field is used to transport magnetic nanoparticles loaded with
Jin Xie et al.
Theranostics, 2, 122-124 (2012-01-31)
This theme issue provides a timely collection of studies on magnetic nanoparticle-based imaging, bio-sensing, therapy and/or their combinations.

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