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17763

Sigma-Aldrich

(+)-Limonene 1,2-epoxide

mixture of cis/trans-isomers, ≥97.0% (sum of isomers, GC)

Synonym(s):

(+)-Limonene epoxide, (+)-p-Mentha-1,8-diene 1,2-epoxide, (4R)-1,2-Epoxy-p-menth-8-ene, (4R)-4-Isopropenyl-1-methyl-1-cyclohexene 1,2-epoxide

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About This Item

Empirical Formula (Hill Notation):
C10H16O
CAS Number:
Molecular Weight:
152.23
Beilstein:
80231
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥97.0% (sum of isomers, GC)

form

liquid

refractive index

n20/D 1.467

density

0.930 g/mL at 20 °C (lit.)

storage temp.

2-8°C

SMILES string

CC(=C)[C@@H]1CCC2(C)OC2C1

InChI

1S/C10H16O/c1-7(2)8-4-5-10(3)9(6-8)11-10/h8-9H,1,4-6H2,2-3H3/t8-,9?,10?/m1/s1

InChI key

CCEFMUBVSUDRLG-XNWIYYODSA-N

General description

(+)-Limonene 1,2-epoxide, a monoterpene that can be prepared from (+)-limonene. It shows potent antinociceptive and antitumoral activity and is mainly used as a building block in synthesis of pharmaceutical products, perfumes, cosmetics and food additives.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

149.0 °F - closed cup

Flash Point(C)

65 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Antonia Amanda C de Almeida et al.
Brain research, 1448, 56-62 (2012-03-01)
The aim of the study is to determine the acute toxicity and anxiolytic-like effects of a mixture of cis and trans of (+)-limonene epoxide in animal models of anxiety. After acute treatment with (+)-limonene epoxide at doses of 25, 50

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