1660000

Thioguanine

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: 6-Thioguanine, 2-Amino-6-mercaptopurine, 2-Amino-6-purinethiol
• Fórmula empírica (notación de Hill): C₅H₅N₅S
• Número CAS: 154-42-7
• Peso molecular: 167.19
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329751279
• MDL number: MFCD00233553
• Beilstein/REAXYS Number: 157765

Propiedades

• grade: pharmaceutical primary standard
• agency: USP
• API family: thioguanine, tioguanine
• manufacturer/tradename: USP
• mp: ≥300 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: NC1=Nc2nc[nH]c2C(=S)N1
• InChI: 1S/C5H5N5S/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)
• InChI key: WYWHKKSPHMUBEB-UHFFFAOYSA-N
• Gene Information: human ... IMPDH1(3614), IMPDH2(3615)

Descripción

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Thioguanine USP Reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as Thioguanine Tablets

Biochem/physiol Actions

Ribosylated and phosphorylated by the same pathway as natural purine bases; as the nucleotide, inhibits a variety of cellular processes involved in nucleic acid synthesis. Has a long history as an effective treatment of leukemia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Información de seguridad

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P301 + P330 + P331 + P310
• Hazard Classifications: Acute Tox. 3 Oral
• Clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable