1604803

Ritonavir

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: 1,3-Thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[[(2S)-3-methyl-2-[[methyl-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]butanoyl]amino]-1,6-diphenylhexan-2-yl]carbamate
• Fórmula empírica (notación de Hill): C₃₇H₄₈N₆O₅S₂
• Número CAS: 155213-67-5
• Peso molecular: 720.94
• MDL number: MFCD08694944
• UNSPSC Code: 41116107
• NACRES: NA.24

Propiedades

• biological source: synthetic
• grade: pharmaceutical primary standard
• agency: USP
• vapor pressure: <0.0000001 kPa ( 25 °C)
• API family: ritonavir
• form: powder
• packaging: pkg of 200 mg
• manufacturer/tradename: USP
• storage condition: protect from light
• color: white to tan
• solubility: acetonitrile: slightly soluble, ethanol: freely soluble, methanol: freely soluble, methylene chloride: freely soluble, water: practically insoluble
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: [s]1c(nc(c1)CN(C)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](C[C@H](O)[C@@H](NC(=O)OCc4[s]cnc4)Cc3ccccc3)Cc2ccccc2)C(C)C
• InChI: 1S/C37H48N6O5S2/c1-24(2)33(42-36(46)43(5)20-29-22-49-35(40-29)25(3)4)34(45)39-28(16-26-12-8-6-9-13-26)18-32(44)31(17-27-14-10-7-11-15-27)41-37(47)48-21-30-19-38-23-50-30/h6-15,19,22-25,28,31-33,44H,16-18,20-21H2,1-5H3,(H,39,45)(H,41,47)(H,42,46)/t28-,31-,32-,33-/m0/s1
• InChI key: NCDNCNXCDXHOMX-XGKFQTDJSA-N

Descripción

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Ritonavir belongs to the group of protease inhibitors that are widely used in combination with other drugs in the prevention of HIV. Its mode of action involves binding to the active site of the protease enzyme and preventing the further maturation of new viral particles.

Application

Ritonavir USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Ritonavir Capsules
• Ritonavir Tablets
• Ritonavir Oral Solution
• Lopinavir and Ritonavir Tablets
• Lopinavir and Ritonavir Oral Solution

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 + H312 + H332
• pcodes: P261 - P280 - P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable