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1335508

USP

Ibuprofen

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

p-Isobutylhydratropic acid, Benzeneacetic acid, α-Methyl-4-(isobutyl)phenylacetic acid, (±)-2-(4-Isobutylphenyl)propanoic acid

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About This Item

Fórmula empírica (notación de Hill):
C13H18O2
Número de CAS:
15687-27-1
Peso molecular:
206.28
MDL number:
MFCD00010393
UNSPSC Code:
41116107
PubChem Substance ID:
329750144
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

ibuprofen

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CC(C)Cc1ccc(cc1)C(C)C(O)=O

InChI

1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)

InChI key

HEFNNWSXXWATRW-UHFFFAOYSA-N

Gene Information

human ... PTGS1(5742) , PTGS2(5743)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ibuprofen USP reference standard suitable for use in specified USP compendial tests and assays.

Also used to prepare standard preparation, standard and standard stock solution for performance tests, assay, identification, and impurity analysis according to the given below monographs of United States Pharmacopeia (USP):
  • Diphenhydramine Hydrochloride and Ibuprofen Capsules
  • Ibuprofen and Pseudoephedrine Hydrochloride Tablets

Biochem/physiol Actions

Cyclooxygenase (COX) inhibitor that has greater activity against COX-1 than against COX-2.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

related product

Referencia del producto
Descripción
Precios

PHR1146

Ibuprofen Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

1335541

Ibuprofen Related Compound C, United States Pharmacopeia (USP) Reference Standard

B1220000

Ibuprofen impurity B, European Pharmacopoeia (EP) Reference Standard

I0020000

Ibuprofen, European Pharmacopoeia (EP) Reference Standard

Y0000140

Ibuprofen impurity F, European Pharmacopoeia (EP) Reference Standard

Y0000881

Ibuprofen for peak identification, European Pharmacopoeia (EP) Reference Standard

61849

2-[4-(2-Methylpropyl)phenyl]ethanol, pharmaceutical impurity standard

1335596

Ibuprofen Related Compound J, United States Pharmacopeia (USP) Reference Standard

PHR1934

Impureza ibuprofeno B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1964

Ibuprofen Impurity F, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1933

Ibuprofen Impurity A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1935

Ibuprofen Impurity N, Pharmaceutical Secondary Standard; Certified Reference Material

BP539

Ibuprofen, British Pharmacopoeia (BP) Reference Standard

BP557

4′-Isobutylacetophenone, British Pharmacopoeia (BP) Reference Standard

PHR2028

Ibuprofen Impurity H, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1965

Ibuprofen Impurity G, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2122

2-(4-Isobutyrylphenyl)propanamide, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2146

2-(4-Isobutylphenyl)-N-(1-phenylethyl)propionamide, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2141

2-(4-Isobutylphenyl)prop-2-enoic Acid, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2136

4-(1-Hydroxy-2-methylpropyl)-acetophenone, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2143

Ibuprofen 2,3-Butylene Glycol Ester, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2142

Ibuprofen 1,3-Butylene Glycol Esters, Pharmaceutical Secondary Standard; Certified Reference Material

BP880

Ibuprofen impurity B, British Pharmacopoeia (BP) Reference Standard

PHR2124

4-Isobutyrylacetophenone, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2145

Ibuprofen 1,2-Propanetriol Esters, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2144

Ibuprofen 1,2-Propylene Glycol Esters, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2483

4-Acetylbenzoic Acid, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2138

Ibuprofen Ethyl Ester

PHR2125

2-(4-Isobutyrylphenyl)propane

PHR2127

2-(4-n-Propylphenyl)propanoic Acid

PHR2129

Isopropyl 2-(4-Isobutylphenyl)propanoate

PHR2130

1-Ethyl-4-isobutylbenzene

PHR2134

4-Isobutylstyrene

PHR2135

1-(4-Isobutylphenyl)ethanol

PHR2132

2-[4-(2-Hydroxy-2-methylpropyl)-phenyl]propanoic Acid, certified reference material, pharmaceutical secondary standard

PHR2137

Ibuprofen Methyl Ester, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2133

Ibuprofen Intermediate, certified reference material, pharmaceutical secondary standard

PHR2126

2-Hydroxypropyl 2-(4-Isobutylphenyl)-propanoate, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2269

4-Isobutylbenzoic acid, Pharmaceutical Secondary Standard; Certified Reference Material

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Acetaminophen United States Pharmacopeia (USP) Reference Standard

USP

1003009

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Ibuprofen Impurity A Pharmaceutical Secondary Standard; Certified Reference Material

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Flurbiprofen United States Pharmacopeia (USP) Reference Standard

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Sigma-Aldrich

401003

(±)-Ibuprofen

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Sigma-Aldrich

375160

(S)-(+)-Ibuprofen

Aspirin United States Pharmacopeia (USP) Reference Standard

USP

1044006

Aspirin

Diphenhydramine Hydrochloride and Ibuprofen Capsules
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 41(2), 1431-1431 (2020)
Ibuprofen and Pseudoephedrine Hydrochloride Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 2286-2286 (2013)
Aleem Adatia et al.
The Journal of pharmacy and pharmacology, 64(5), 626-636 (2012-04-05)
We review the pharmacological properties and clinical evidence pertaining to the efficacy of ibuprofen as a first-line treatment in hip and knee osteoarthritis (OA). In the context of our previous paper's exploration of the aetiology and pathogenesis of OA as
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The fundamental studies for the binding events of protein and its partner are crucial in drug development. In this study, a novel technology named microscale thermophoresis (MST) was applied in the investigation of molecular interaction between an organic dye fluorescein
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The Cochrane database of systematic reviews, 10(10), CD007550-CD007550 (2013-10-24)
This review is an update of a previously published review in The Cochrane Database of Systematic Reviews Issue 3, 2009 on single dose oral dexibuprofen (S(+)-ibuprofen) for acute postoperative pain in adults.Dexibuprofen is a non-steroidal anti-inflammatory drug (NSAID) licensed for
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