1316004

Hydrocortisone

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione, 17-Hydroxycorticosterone, 4-Pregnene-11β,17α,21-triol-3,20-dione, Cortisol, Kendall’s compound F, Reichstein’s substance M
• Fórmula empírica (notación de Hill): C₂₁H₃₀O₅
• Número de CAS: 50-23-7
• Peso molecular: 362.46
• Beilstein: 1354819
• Número MDL: MFCD00011654
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329750063
• NACRES: NA.24

Propiedades

• grado: pharmaceutical primary standard
• familia API: hydrocortisone
• fabricante / nombre comercial: USP
• mp: 211-214 °C (lit.)
• aplicaciones: pharmaceutical (small molecule)
• Formato: neat
• cadena SMILES: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)CO
• InChI: 1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
• Clave InChI: JYGXADMDTFJGBT-VWUMJDOOSA-N
• Información sobre el gen: human ... NR3C1(2908)

Descripción

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Hydrocortisone USP reference standard suitable for use in specified USP compendial quality tests and assays.

Also used to prepare standard stock, standard, and system suitability solution for assay, identification, and performance test by liquid chromatography in accordance with the given below monographs of United States Pharmacopeia (USP) :

• Hydrocortisone Sodium Succinate for Injection
• Hydrocortisone Tablets
• Hydrocortisone Gel
• Hydrocortisone Lotion

Acciones bioquímicas o fisiológicas

Primary glucocorticoid secreted by the adrenal cortex. It has three times the anti-inflammatory potency of corticosterone but much lower Na²⁺ retention potency.

Primary glucocorticoid secreted by the adrenal cortex.

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Otras notas

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS08
• Palabra de señalización: Danger
• Frases de peligro: H360Df,H373
• Consejos de prudencia: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Clasificaciones de peligro: Repr. 1A - STOT RE 2
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable